Results 51 to 60 of about 266 (95)
mBio, 2020 Many bacterial pathogens coexist with host organisms, rarely causing disease while adapting to host responses. Neisseria meningitidis, a major cause of meningitis and septicemia, is a frequent persistent colonizer of asymptomatic teenagers/young adults ...
Luke R. Green +8 more
semanticscholar +1 more source
Scientific Reports, 2016 Neisseria meningitidis is a human-specific bacterium that varies in invasive potential. All meningococci are carried in the nasopharynx, and most genotypes are very infrequently associated with invasive meningococcal disease; however, those belonging to ...
A. Tan +6 more
semanticscholar +1 more source
Kinetic, Catalytic and Epigenetic Properties of HpyAXVII DNA Methyltransferase – a Phasevarion in the Human Pathogen Helicobacter pylori [PDF]
, 2019 Helicobacter pylori is the leading cause of gastric cancer in human beings. It is a helix-shaped, Gram-negative, motile bacteria that colonizes the gastric mucosa and eventually the gastric epithelium. It has an overabundance of Restriction-Modification (
Prasad, Yedu
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A novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44 [PDF]
, 2011 Neisseria meningitidis is a major cause of septicemia and meningitis. The hypervirulent clonal complex 41/44 (cc41/44) has emerged as the predominant cause of serogroup B meningococcal disease, having been responsible for recent outbreaks and epidemics ...
Gawthorne, Jayde +16 more
core +1 more source
Broad Conditions Favor the Evolution of Phase-Variable Loci [PDF]
, 2016 Simple sequence repeat (SSR) tracts produce stochastic on-off switching, or phase variation, in the expression of a panoply of surface molecules in many bacterial commensals and pathogens.
Palmer, Mark +3 more
core +1 more source
Mechanistic and functional analysis of Cj0031: a phase variable methyltransferase in Campylobacter jejuni [PDF]
, 2013 Campylobacter jejuni constitutes the major cause of food-borne diarrheal disease in developed countries. The genome of this species comprises many surface genes having mononucleotide repeat tracts (PolyG/PolyC) which undergo reversible switching between ...
Awais Anjum (7636874)
core
Discovery Projects - Grant ID: DP180100976 [PDF]
Phase-variable epigenetic regulators in bacterial veterinary pathogens. This project aims to identify phasevarion regulated genes in the major bacterial swine pathogens Streptococcus suis and Actinobacillus pleuropneumoniae. Both species contain randomly
core
Phase variation and adaptation in bacteria: a 'Red Queen's Race' [PDF]
, 2011 In nature, bacteria are constantly exposed to many stressful conditions of life. This is particularly true of pathogens. Survival and adaptation under stressful conditions demand multiple strategies, genetic as well as phenotypic. Bacteria have many, pre-
Jayaraman, R.
core +2 more sources
Phasevarions of pathogenic Neisseria [PDF]
Certain bacterial DNA repeats are prone to hyper mutation. Genes with these repeats, Contingency genes, are randomly switched on and off. This process, phase variation , generates diversity in a population.
core
Phase variable methyltransferases and their role in gene regulation in pathogenic bacteria [PDF]
, 2009 Previous work carried out in our laboratory has identified that phase variation of type III R-M systems found in Haemophilus influenzae, Neisseria meningitidis and N. gonorrhoeae is reversible, and occurs at high frequency, as seen both through mod::lacZ
Stefanie Dowideit
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