Broad Conditions Favor the Evolution of Phase-Variable Loci [PDF]
Simple sequence repeat (SSR) tracts produce stochastic on-off switching, or phase variation, in the expression of a panoply of surface molecules in many bacterial commensals and pathogens.
Palmer, Mark +3 more
core +1 more source
Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that control distinct phasevarions. [PDF]
Nahar N +16 more
europepmc +1 more source
Helicobacter pylori is the leading cause of gastric cancer in human beings. It is a helix-shaped, Gram-negative, motile bacteria that colonizes the gastric mucosa and eventually the gastric epithelium. It has an overabundance of Restriction-Modification (
Prasad, Yedu
core
Streptococcus suis Encodes Multiple Allelic Variants of a Phase-Variable Type III DNA Methyltransferase, ModS, That Control Distinct Phasevarions. [PDF]
Tram G +7 more
europepmc +1 more source
Novel Identification of Bacterial Epigenetic Regulations Would Benefit From a Better Exploitation of Methylomic Data. [PDF]
Payelleville A, Brillard J.
europepmc +1 more source
Neisseria meningitidis is a major cause of septicemia and meningitis. The hypervirulent clonal complex 41/44 (cc41/44) has emerged as the predominant cause of serogroup B meningococcal disease, having been responsible for recent outbreaks and epidemics ...
Gawthorne, Jayde +16 more
core +1 more source
No Change, No Life? What We Know about Phase Variation in Staphylococcus aureus. [PDF]
Gor V, Ohniwa RL, Morikawa K.
europepmc +1 more source
Discovery Projects - Grant ID: DP180100976
Phase-variable epigenetic regulators in bacterial veterinary pathogens. This project aims to identify phasevarion regulated genes in the major bacterial swine pathogens Streptococcus suis and Actinobacillus pleuropneumoniae. Both species contain randomly
core
Phasevarions of pathogenic Neisseria
Certain bacterial DNA repeats are prone to hyper mutation. Genes with these repeats, Contingency genes, are randomly switched on and off. This process, phase variation , generates diversity in a population.
core
High-depth RNA-seq data to investigate gene regulation mediated by phase-variable DNA methyltransferases in serogroup B <i>Neisseria meningitidis</i>. [PDF]
Ascari A +3 more
europepmc +1 more source

