Results 111 to 120 of about 23,945 (282)

Phasic stress measures and thought intrusions resulting from distress and cognitive inhibition [PDF]

, 1994
Recently, a revitalized interest in the effects of cognitive inhibition and its implications for psychological and physical health has emerged. Some researchers believe that inhibition is difficult, fosters subsequent incursions of the inhibited thought,
Kuntz, Todd Arthur
core  

Albumin-Oleic Acid Promotes Phasic Inhibition of Early and Late Tibialis Anterior Reflex Activity following SCI. [PDF]

, 2013
Analysis of the first and second phase of Tibialis Anterior (TA) reflex temporal summation in naïve animals (Fig. 4A) and those with SCI 28 days after T9 spinal contusion (Cont) revealed that the synergistic phasic inhibitory effect of Albumin-Oleic acid
Gerardo Avila-Martin (341068), Julio Gómez-Soriano (341070), Julian Taylor (341071), Iriana Galan-Arriero (341069)   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The control of locomotor frequency by excitation and inhibition [PDF]

, 2012
Every type of neural rhythm has its own operational range of frequency. Neuronal mechanisms underlying rhythms at different frequencies, however, are poorly understood.
Li, Wen-Chang, Moult, Peter Robert, Li, Wenchang, Moult, Peter R.   +3 more
core   +1 more source

Antinociceptive effect of intrathecal neostigmine evaluated in rats by two different pain models

Brazilian Journal of Medical and Biological Research, 1997
The analgesic efficacy of cholinergic agonists and anticholinesterase agents has been widely recognized. The analgesic effect obtained by activating cholinergic mechanisms, however, seems to depend on the experimental pain model utilized for its ...
Prado W.A., Gonçalves A.S.
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Age-related decrease in motor cortical inhibition during standing under different sensory conditions [PDF]

, 2014
BackgroundAlthough recent studies point to the involvement of the primary motor cortex in postural control, it is unknown if age-related deterioration of postural control is associated with changes in motor cortical circuits.
Hortobágyi, Tibor, Taube, Wolfgang, Stéphane eBaudry, Tibor eHortobágyi, Tibor Hortobágyi, Hortobagyi, Tibor; id_orcid, Margot Hogenhout, Wolfgang eTaube, Stéphane Baudry, Baudry, Stéphane, Margot eHogenhout, Selma Papegaaij, Wolfgang Taube, Selma ePapegaaij, Papegaaij, Selma, Hogenhout, Margot   +15 more
core   +1 more source

Extrasynaptic α6 subunit-containing GABAA receptors modulate excitability in turtle spinal motoneurons.

PLoS ONE, 2014
Motoneurons are furnished with a vast repertoire of ionotropic and metabotropic receptors as well as ion channels responsible for maintaining the resting membrane potential and involved in the regulation of the mechanisms underlying its membrane ...
Carmen Andres, Justo Aguilar, Ricardo González-Ramírez, David Elias-Viñas, Ricardo Felix, Rodolfo Delgado-Lezama   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABAA receptors

Cell Reports
Summary: Striatal dopamine axons co-release dopamine and gamma-aminobutyric acid (GABA), using GABA provided by uptake via GABA transporter-1 (GAT1). Functions of GABA co-release are poorly understood.
Jyoti C. Patel, Ang D. Sherpa, Riccardo Melani, Paul Witkovsky, Madeline R. Wiseman, Brian O’Neill, Chiye Aoki, Nicolas X. Tritsch, Margaret E. Rice   +8 more
doaj   +1 more source