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Drug and Therapeutics Bulletin, 1962
Phenacetin (or acetophenetidin), alone and in combination with other drugs, has been used liberally as an analgesic and antipyretic since its introduction into medical prectice in 1887, and has generally been considered a relatively safe drug (P. K.
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Phenacetin (or acetophenetidin), alone and in combination with other drugs, has been used liberally as an analgesic and antipyretic since its introduction into medical prectice in 1887, and has generally been considered a relatively safe drug (P. K.
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Urology, 1975
Prolonged ingestion of mixed analgesics containing phenacetin has been associated significantly with the development of a chronic interstitial nephritis frequently associated with papillary necrosis. This disease is frequently underdiagnosed. If an adequate history of headache and/or backache (of which most of these patients complain) is not taken, the
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Prolonged ingestion of mixed analgesics containing phenacetin has been associated significantly with the development of a chronic interstitial nephritis frequently associated with papillary necrosis. This disease is frequently underdiagnosed. If an adequate history of headache and/or backache (of which most of these patients complain) is not taken, the
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The Journal of Clinical Pharmacology and New Drugs, 1971
Daily administration of .29 gm/kg per day phenacetin to male albino rats for 220 days had no effect on body weight food and water intake colonic temperature and the volume or composition of urine. Then were no deaths and no evidence of pathologological lesions in the liver or kidneys or increased susceptibility to infections.
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Daily administration of .29 gm/kg per day phenacetin to male albino rats for 220 days had no effect on body weight food and water intake colonic temperature and the volume or composition of urine. Then were no deaths and no evidence of pathologological lesions in the liver or kidneys or increased susceptibility to infections.
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Journal of Endodontics, 1979
Phenacetin, or its derivative acetaminophen, is an extremely common and increasingly used substitute for aspirin. Although the drug is mild and effective, its toxicity is less obvious and less manageable than that of aspirin.
G F, Valle +2 more
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Phenacetin, or its derivative acetaminophen, is an extremely common and increasingly used substitute for aspirin. Although the drug is mild and effective, its toxicity is less obvious and less manageable than that of aspirin.
G F, Valle +2 more
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Drugs, 1986
Since their synthesis in the late 1800s paracetamol (acetaminophen) and phenacetin have followed divergent pathways with regard to their popularity as mild analgesic/antipyretic drugs. Initially, paracetamol was discarded in favour of phenacetin because the latter drug was supposedly less toxic.
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Since their synthesis in the late 1800s paracetamol (acetaminophen) and phenacetin have followed divergent pathways with regard to their popularity as mild analgesic/antipyretic drugs. Initially, paracetamol was discarded in favour of phenacetin because the latter drug was supposedly less toxic.
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