Results 11 to 20 of about 5,776 (241)

Cavity ring down spectroscopy of cold neutral phenanthrene and phenanthridine in supersonic jets

open access: yesAIP Advances, 2019
Here we study the effect of nitrogen insertion on the electronic spectra of polycyclic aromatic hydrocarbon (PAH) molecules measured under laboratory conditions that are relevant for comparison with astronomical data.
Salma Bejaoui, Farid Salama
doaj   +2 more sources

The Aza-Analogous Benzo[c]phenanthridine P8-D6 Acts as a Dual Topoisomerase I and II Poison, thus Exhibiting Potent Genotoxic Properties

open access: yesMolecules, 2020
The benzo[c]phenanthridine P8-D6 was recently found to suppress the catalytic activity of both human topoisomerase (Topo) I and II. Concomitantly, potent cytotoxic activity was observed in different human tumor cell lines, raising questions about the ...
Georg Aichinger   +6 more
doaj   +2 more sources

QSAR Modeling on Benzo[<em>c</em>]phenanthridine Analogues as Topoisomerase I Inhibitors and Anti-cancer Agents [PDF]

open access: goldMolecules, 2012
Benzo[<em>c</em>]phenanthridine (BCP) derivatives were identified as topoisomerase I (TOP-I) targeting agents with pronounced antitumor activity.
Thi-Ngoc-Phuong Huynh   +3 more
doaj   +2 more sources

Discovery of benzo[c]phenanthridine derivatives with potent activity against multidrug-resistant Mycobacterium tuberculosis [PDF]

open access: yesMicrobiology Spectrum
Mycobacterium tuberculosis (Mtb), the pathogen responsible for tuberculosis (TB), is the leading cause of bacterial disease-related death worldwide. Current antibiotic regimens for the treatment of TB remain dated and suffer from long treatment times as ...
Yi Chu Liang   +9 more
doaj   +2 more sources

Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2

open access: bronzeEuropean Journal of Medicinal Chemistry, 2021
Yi‐Ting Wang   +14 more
openalex   +3 more sources

Design, synthesis and biological evaluation of phenanthridine amide and 1,2,3-triazole analogues against Mycobacterium tuberculosis. [PDF]

open access: greenRSC Med Chem, 2023
Nandikolla A   +9 more
europepmc   +3 more sources

THE ANTIBACTERIAL ACTIVITY OF PHENANTHRIDINE COMPOUNDS [PDF]

open access: bronzeBritish Journal of Pharmacology and Chemotherapy, 1954
A, SEAMAN, M, WOODBINE
openaire   +4 more sources

Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation

open access: bronzeChemico-Biological Interactions, 2020
Daniela Marasco   +9 more
openalex   +3 more sources

In Pursuit of Low Energy Phosphorescence: Late Metal Coordination Complexes of the Planar, π-extended Bipyridyl Ligand 6,6',7,7'-Biphenanthridine. [PDF]

open access: yesChemistry
Abstract The coordination chemistry of the planar, doubly π‐extended bipyridine analog, 6,6′,7,7′‐biphenanthridine (p‐biphe), is presented. The phenanthridine units in p‐biphe are fused together at the 6‐ and 7‐ positions, and the resulting rigid ligand is compared with the more flexible parent “biphe” fused only at the 6‐positions.
Nemez DB   +4 more
europepmc   +2 more sources

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