Results 11 to 20 of about 5,641 (202)

Site-Selective Ligand Functionalization Reverses Hypsochromic Luminescence Shifts in Platinum(II) Complexes of Benzannulated NCN-Coordinating Ligands. [PDF]

Chemistry
Reversing the Trend: Phenanthridine (benzo[c]quinoline) donors defy conventional logic that increasing ligand benzannulation leads to bathochromic (red) shifts in the absorption and emission of their coordination complexes. Here, we provide a counterfactual that reverses this trend: substitution at the phenanthridine 6‐position (i.
Ortiz RJ, Garcia-Torres E, Brothwood PL, Williams JAG, Herbert DE.   +4 more
europepmc   +2 more sources

Pyrrolo‐Fused Phenanthridines as Potential Anticancer Agents: Synthesis, Prediction, and Biological Evaluation [PDF]

J Biochem Mol Toxicol
ABSTRACT We report the synthesis of four novel monoquaternary salts and four fused pyrrolo‐phenanthridine compounds, fully characterized by NMR, FT‐IR, and mass spectrometry. Guided by theoretical predictions, including molecular docking studies, we assessed their cytotoxic activity and biocompatibility.
Al‐Matarneh A, Simionescu N, Nicolescu A, Cibotariu N, Danac R, Al‐Matarneh M, Mangalagiu I.   +6 more
europepmc   +2 more sources

Diversified Fluoroalkylation of Alkenes Using Quaternary Fluoroalkyl Alcohols as the Fluoroalkylating Reagents. [PDF]

Adv Sci (Weinh)
A universal photoredox‐catalyzed fluoroalkylation approach by utilizing new (fluoroalkyl)diaryl methanols as versatile fluoroalkylating reagents is developed. This protocol facilitates the synthesis of mono‐, di‐, tri‐, and even polyfluoroalkylation of a broad scope of alkenes.
Lu H, Fan Z, Zou Y, Zhang A.
europepmc   +2 more sources

Structure-activity relationships of synthetic analogs of jasmonic acid and coronatine on induction of benzo[c]phenanthridine alkaloid accumulation in Eschscholzia californica cell cultures [PDF]

, 2000
A facile test system based on the accumulation of benzo[c]phenanthridine alkaloids in Eschscholzia californica cell suspension culture (an indicator of defense gene activation) has been used to analyze a series of synthetic compounds for elicitor-like ...
Dzink J.L., Holbrook L., Kutchan T.M., Quinkert G., Rosco A., Yamane H.   +5 more
core   +1 more source

Fluorescent Carbazole-Derived Aza[5]Helicenes: Synthesis, Functionalization, and Characterization. [PDF]

Chemistry
Variously substituted indolophenanthridines, indolocarbazoles, and cinnolinocarbazoles synthesized by ortho fusion from teraryl precursors show significant Stokes shifts, especially for the protonated states of indolophenanthridines and cinnolinocarbazole.
Marten I, Dilanas MEA, Podlech J.
europepmc   +2 more sources

Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]

, 2014
It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer, Agbe, Bruhn, Brun, Cristodero, Dean, Deterding, Herbert, Hoare, Holmes, Kaminsky, Lai, Lanteri, M. K. Gould, Mathis, Mukherjee, Painter, Priest, Roy Chowdhury, Räz, Schnaufer, Schnaufer, Schnaufer, Shapiro, Stuart, Tang, Thuita, Ward, Wenzler, Wenzler, Wilson, Zhang, Zuma   +32 more
core   +1 more source

An electron-deficient triosmium cluster containing the thianthrene ligand: Synthesis, structure and reactivity of [Os₃(CO)₉(μ3-η2-C₁₂H₇S₂)(μ-H)] [PDF]

, 2008
Reaction of [Os₃(CO)₁₀(CH₃CN)₂] with thianthrene at 80 °C leads to the nonacarbonyl dihydride compound [Os₃(CO)₉(μ-3,4-η²-C₁₂H₆S₂)(μ-H)₂] (1) and the 46-electron monohydride compound [Os₃(CO)₉(μ₃-η²-C₁₂H₇S₂)(μ-H)] (2).
Hassan, Mohammad R., Kabir, Shariff E., Karim, Md. Manzurul, Nicholson, Brian K., Raha, Arun K., Rosenberg, Edward, Salassa, Luca, Sharmin, Ayesha   +7 more
core   +1 more source

A radical addition/cyclization of diverse ethers to 2-isocyanobiaryls under mildly basic aqueous conditions [PDF]

, 2016
Mildly basic aqueous conditions facilitated the tert-butyl peroxybenzoate (TBPB) mediated dehydrogenative addition of a range of ethers, including acetals, to diverse substituted 2-isocyanobiaryls. Mechanistic studies suggest that this radical cascade is
Anton-Torrecillas, Cintia, Felipe-Blanco, Diego, Gonzalez-Gomez, Jose C.   +2 more
core   +2 more sources

Analysis of benzo[c] phenanthridine alkaloids in Eschscholtzia californica cell culture using HPLC-DAD and HPLC-ESI-MS/MS [PDF]

, 2014
Effective HPLC-DAD and HPLC-ESI-MS/MS methods have been developed for the analysis of eight benzo[c] phenanthridine alkaloids (sanguinarine, chelirubine, macarpine, chelerythrine, dihydrosanguinarine, dihydrochelirubine, dihydromacarpine and ...
Hong Soon Rhee, Jong Moon Park, Min Woo Lee, Schumacher HM, Seok Young Son   +4 more
core   +1 more source

Nitrogen‐Centered Organic Persistent Radicals Catalyze Redox‐Neutral C─C Bond Forming Reactions

Angewandte Chemie, Volume 137, Issue 33, August 11, 2025.
Kuhn verdazyls, discovered over 60 years ago, are shown as effective catalysts for the first time. Their tunable redox properties enable organocatalytic redox‐neutral C─H arylation and C─H trifluoromethylation reactions without light activation.
Shrouq Mujahed, Jaysan Janabel, Kundan Shaw, Roberta Cagliani, Tynchtyk Amatov   +4 more
wiley   +2 more sources