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Pyrazine and Phenazine Heterocycles: Platforms for Total Synthesis and Drug Discovery
There are numerous pyrazine and phenazine compounds that demonstrate biological activities relevant to the treatment of disease. In this review, we discuss pyrazine and phenazine agents that have shown potential therapeutic value, including several ...
Robert W. Huigens +4 more
doaj +4 more sources
Analysis of genetic information from soil samples provides insights into bacteria that help to protect crops from fungal diseases by producing chemicals called phenazines.
Sarah J Wolfson, Libusha Kelly
doaj +3 more sources
Pseudomonas fluorescens 9 and Bacillus subtilis 54, proposed as biofungicides to control Macrophomina phaseolina, a dangerous pathogen of soybean and other crops, were grown in vitro to evaluate their ability to produce metabolites with antifungal ...
Stefany Castaldi +7 more
doaj +2 more sources
Phenazines are natural bacterial antibiotics that can protect crops from disease. However, for most crops it is unknown which producers and specific phenazines are ecologically relevant, and whether phenazine biodegradation can counter their effects.
Daniel Dar +3 more
doaj +2 more sources
Ultrastable aqueous phenazine flow batteries with high capacity operated at elevated temperatures
Pan Wang, Yunlong Ji
exaly +2 more sources
Quorum sensing modulates microbial community structure through regulation of secondary metabolites [PDF]
Bacteria are recognized for their diverse metabolic capabilities, yet the impact of microbe-microbe interactions on multispecies community structure and dynamics is poorly understood.
April C. Armes +9 more
doaj +2 more sources
Application of plant growth promoting bacteria may induce plant salt stress tolerance, however the underpinning microbial and plant mechanisms remain poorly understood.
Peiguo Yuan +7 more
doaj +2 more sources
Phenazine compounds are widely used in agricultural control and the medicine industry due to their high inhibitory activity against pathogens and antitumor activity.
Yu-Xuan Li +9 more
doaj +1 more source
Phenazines are redox‐active secondary metabolites produced by diverse bacteria including the opportunistic pathogen Pseudomonas aeruginosa. Extracellular electron transfer via phenazines enhances anaerobic survival by serving as an electron sink for ...
John A. Ciemniecki, D. Newman
semanticscholar +1 more source
Identification of the Lomofungin Biosynthesis Gene Cluster and Associated Flavin-Dependent Monooxygenase Gene in Streptomyces lomondensis S015. [PDF]
Streptomyces lomondensis S015 synthesizes the broad-spectrum phenazine antibiotic lomofungin. Whole genome sequencing of this strain revealed a genomic locus consisting of 23 open reading frames that includes the core phenazine biosynthesis gene cluster ...
Chunxiao Zhang +5 more
doaj +1 more source

