Results 1 to 10 of about 30,855 (205)

Pyrazine and Phenazine Heterocycles: Platforms for Total Synthesis and Drug Discovery

open access: yesMolecules, 2022
There are numerous pyrazine and phenazine compounds that demonstrate biological activities relevant to the treatment of disease. In this review, we discuss pyrazine and phenazine agents that have shown potential therapeutic value, including several ...
Robert W. Huigens   +4 more
doaj   +4 more sources

Finding phenazine

open access: yeseLife, 2020
Analysis of genetic information from soil samples provides insights into bacteria that help to protect crops from fungal diseases by producing chemicals called phenazines.
Sarah J Wolfson, Libusha Kelly
doaj   +3 more sources

Pseudomonas fluorescens Showing Antifungal Activity against Macrophomina phaseolina, a Severe Pathogenic Fungus of Soybean, Produces Phenazine as the Main Active Metabolite

open access: yesBiomolecules, 2021
Pseudomonas fluorescens 9 and Bacillus subtilis 54, proposed as biofungicides to control Macrophomina phaseolina, a dangerous pathogen of soybean and other crops, were grown in vitro to evaluate their ability to produce metabolites with antifungal ...
Stefany Castaldi   +7 more
doaj   +2 more sources

Global landscape of phenazine biosynthesis and biodegradation reveals species-specific colonization patterns in agricultural soils and crop microbiomes

open access: yeseLife, 2020
Phenazines are natural bacterial antibiotics that can protect crops from disease. However, for most crops it is unknown which producers and specific phenazines are ecologically relevant, and whether phenazine biodegradation can counter their effects.
Daniel Dar   +3 more
doaj   +2 more sources

Quorum sensing modulates microbial community structure through regulation of secondary metabolites [PDF]

open access: yesmSphere
Bacteria are recognized for their diverse metabolic capabilities, yet the impact of microbe-microbe interactions on multispecies community structure and dynamics is poorly understood.
April C. Armes   +9 more
doaj   +2 more sources

Phenazine-Producing Rhizobacteria Promote Plant Growth and Reduce Redox and Osmotic Stress in Wheat Seedlings Under Saline Conditions

open access: yesFrontiers in Plant Science, 2020
Application of plant growth promoting bacteria may induce plant salt stress tolerance, however the underpinning microbial and plant mechanisms remain poorly understood.
Peiguo Yuan   +7 more
doaj   +2 more sources

Economical Production of Phenazine-1-carboxylic Acid from Glycerol by Pseudomonas chlororaphis Using Cost-Effective Minimal Medium

open access: yesBiology, 2023
Phenazine compounds are widely used in agricultural control and the medicine industry due to their high inhibitory activity against pathogens and antitumor activity.
Yu-Xuan Li   +9 more
doaj   +1 more source

NADH dehydrogenases are the predominant phenazine reductases in the electron transport chain of Pseudomonas aeruginosa

open access: yesMolecular Microbiology, 2023
Phenazines are redox‐active secondary metabolites produced by diverse bacteria including the opportunistic pathogen Pseudomonas aeruginosa. Extracellular electron transfer via phenazines enhances anaerobic survival by serving as an electron sink for ...
John A. Ciemniecki, D. Newman
semanticscholar   +1 more source

Identification of the Lomofungin Biosynthesis Gene Cluster and Associated Flavin-Dependent Monooxygenase Gene in Streptomyces lomondensis S015. [PDF]

open access: yesPLoS ONE, 2015
Streptomyces lomondensis S015 synthesizes the broad-spectrum phenazine antibiotic lomofungin. Whole genome sequencing of this strain revealed a genomic locus consisting of 23 open reading frames that includes the core phenazine biosynthesis gene cluster ...
Chunxiao Zhang   +5 more
doaj   +1 more source

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