Results 11 to 20 of about 47,486 (283)
Frontiers in Bioengineering and Biotechnology, 2020 Pseudomonas putida KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways.
Isabel Bator +8 more
doaj +2 more sources
Spatial heterogeneity in biofilm metabolism elicited by local control of phenazine methylation
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Pseudomonas aeruginosa causes biofilm-based infections and is known for its production of colorful phenazine derivatives. Among these, the methylated phenazines are the most toxic and can cause condition-dependent damage to their producer ...
Christopher R. Evans +8 more
semanticscholar +1 more source
Pharmaceutics, 2021 Heat shock protein 27 (Hsp27) has an established role in tumor progression and chemo-resistance of castration-resistant prostate cancer (CRPC). Hsp27 protects eukaryotic translation initiation factor 4E (eIF4E) from degradation, thereby maintaining ...
Hajer Ziouziou +13 more
doaj +1 more source
Genomic characterization of a new endophytic Streptomyces kebangsaanensis identifies biosynthetic pathway gene clusters for novel phenazine antibiotic production [PDF]
PeerJ, 2017 Background Streptomyces are well known for their capability to produce many bioactive secondary metabolites with medical and industrial importance. Here we report a novel bioactive phenazine compound, 6-((2-hydroxy-4-methoxyphenoxy) carbonyl) phenazine-1-
Juwairiah Remali +6 more
doaj +2 more sources
Predicting the Redox Potentials of Phenazine Derivatives Using DFT-Assisted Machine Learning
ACS Omega, 2022 This study investigates four machine-learning (ML) models to predict the redox potentials of phenazine derivatives in dimethoxyethane using density functional theory (DFT).
Siddharth Ghule +4 more
semanticscholar +1 more source
Frontiers in Microbiology, 2021 Antibiotic-producing microorganisms have developed several self-resistance mechanisms to protect them from autotoxicity. Transporters belonging to the resistance- nodulation-division (RND) superfamily commonly confer multidrug resistance in Gram-negative
Yangyang Zhao +9 more
doaj +1 more source
ACS Infectious Diseases, 2022 During infection, bacteria use an arsenal of resistance mechanisms to negate antibiotic therapies. In addition, pathogenic bacteria form surface-attached biofilms bearing enriched populations of metabolically dormant persister cells.
Ke Liu +8 more
semanticscholar +1 more source
Screening of natural phenazine producers for electroactivity in bioelectrochemical systems
Microbial Biotechnology, 2022 Mediated extracellular electron transfer (EET) might be a great vehicle to connect microbial bioprocesses with electrochemical control in stirred‐tank bioreactors.
Ángel G. Franco +2 more
semanticscholar +1 more source
Genetic Approach for the Fast Discovery of Phenazine Producing Bacteria
Marine Drugs, 2011 A fast and efficient approach was established to identify bacteria possessing the potential to biosynthesize phenazines, which are of special interest regarding their antimicrobial activities.
Johannes F. Imhoff +3 more
doaj +1 more source
Microbiology Spectrum, 2023 Myxin, a di-N-oxide phenazine isolated from the soil bacterium Lysobacter antibioticus, exhibits potent activity against various microorganisms and has the potential to be developed as an agrochemical.
Yangyang Zhao +4 more
doaj +1 more source