Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin +8 more
wiley +1 more source
Traditional Chinese Herbal Plant Penthorum chinense Pursh: Health Factors and Its Future Development
This review expounds on the species, morphological characteristics, and distribution areas of Penthorum chinense Pursh, summarizes the active ingredients mainly including flavonoids in PCP and their extraction methods. It also pays particular attention to the pharmacological effects of PCP, such as liver protection, antioxidation, anti‐inflammation ...
Hui Zhang, Ning Zhang, Baoguo Sun
wiley +1 more source
ABSTRACT Objective Digital interventions designed to prevent development of chronic pain and comorbid mental health symptoms, specifically targeting the acute injury recovery period, are in the early stages of development. The evidence‐based PTSD Coach mobile application is a free resource offering cognitive‐behavioral interventions to self‐manage ...
Maria L. Pacella‐LaBarbara +7 more
wiley +1 more source
Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
Clinical Issues Associated with Urine Testing of Substances of Abuse [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90147/1/j.1875-9114.1997.tb03059.x ...
Eskridge, Kimberly D., Guthrie, Sally K.
core +1 more source
Mobilisation Alarm Use in Hospitals and Alignment With Person‐Centred Practice: A Qualitative Study
ABSTRACT Aim To explore why and how staff use alarms for falls prevention in hospital and their alignment to person‐centred practice. Design Qualitative interpretive design. Methods One hundred focus groups and 25 interviews across 10 health services were completed between October 2022 and September 2024.
Kelly Stephen +3 more
wiley +1 more source
What common substances can cause false positives on urine screens for drugs of abuse? [PDF]
False-positive reports on urine drug screens by immunoassay are rare (strength of recommendation [SOR]: C, small controlled-exposure studies, small case series).
Goodwin, Cheryl +2 more
core
Adolescent brain cognitive development (ABCD) study: Overview of substance use assessment methods. [PDF]
One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and
Bartsch, Hauke +9 more
core +2 more sources
The landscape of dementia research, diagnosis, treatment, and care in Latin America
Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto +41 more
wiley +1 more source
ABSTRACT Background and Aims Families of children with special needs face sustained emotional, psychological, and social challenges that can profoundly influence both caregiver well‐being and child health outcomes. Primary care clinicians are uniquely positioned to address these needs longitudinally, yet the psychosocial dimensions remain under ...
Muhammad Husnain Ahmad +10 more
wiley +1 more source

