Results 51 to 60 of about 10,621 (203)

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

open access: yesExperimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin   +8 more
wiley   +1 more source

Traditional Chinese Herbal Plant Penthorum chinense Pursh: Health Factors and Its Future Development

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This review expounds on the species, morphological characteristics, and distribution areas of Penthorum chinense Pursh, summarizes the active ingredients mainly including flavonoids in PCP and their extraction methods. It also pays particular attention to the pharmacological effects of PCP, such as liver protection, antioxidation, anti‐inflammation ...
Hui Zhang, Ning Zhang, Baoguo Sun
wiley   +1 more source

A Qualitative Exploration of Post‐Injury Challenges and the Potential Role of the PTSD Coach Mobile Application to Improve Recovery Among Acutely Injured Patients

open access: yesJournal of Clinical Psychology, Volume 82, Issue 4, Page 521-534, April 2026.
ABSTRACT Objective Digital interventions designed to prevent development of chronic pain and comorbid mental health symptoms, specifically targeting the acute injury recovery period, are in the early stages of development. The evidence‐based PTSD Coach mobile application is a free resource offering cognitive‐behavioral interventions to self‐manage ...
Maria L. Pacella‐LaBarbara   +7 more
wiley   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen   +2 more
wiley   +1 more source

Clinical Issues Associated with Urine Testing of Substances of Abuse [PDF]

open access: yes, 1997
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90147/1/j.1875-9114.1997.tb03059.x ...
Eskridge, Kimberly D., Guthrie, Sally K.
core   +1 more source

Mobilisation Alarm Use in Hospitals and Alignment With Person‐Centred Practice: A Qualitative Study

open access: yesJournal of Advanced Nursing, Volume 82, Issue 4, Page 3489-3508, April 2026.
ABSTRACT Aim To explore why and how staff use alarms for falls prevention in hospital and their alignment to person‐centred practice. Design Qualitative interpretive design. Methods One hundred focus groups and 25 interviews across 10 health services were completed between October 2022 and September 2024.
Kelly Stephen   +3 more
wiley   +1 more source

What common substances can cause false positives on urine screens for drugs of abuse? [PDF]

open access: yes, 2006
False-positive reports on urine drug screens by immunoassay are rare (strength of recommendation [SOR]: C, small controlled-exposure studies, small case series).
Goodwin, Cheryl   +2 more
core  

Adolescent brain cognitive development (ABCD) study: Overview of substance use assessment methods. [PDF]

open access: yes, 2018
One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and
Bartsch, Hauke   +9 more
core   +2 more sources

The landscape of dementia research, diagnosis, treatment, and care in Latin America

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto   +41 more
wiley   +1 more source

The Emotional and Psychological Impact on Families Raising Children With Special Needs: A Primary Care Perspective

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Families of children with special needs face sustained emotional, psychological, and social challenges that can profoundly influence both caregiver well‐being and child health outcomes. Primary care clinicians are uniquely positioned to address these needs longitudinally, yet the psychosocial dimensions remain under ...
Muhammad Husnain Ahmad   +10 more
wiley   +1 more source

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