Results 91 to 100 of about 8,267 (256)
Bipolar Disorders, Volume 27, Issue 5, Page 347-357, August 2025.ABSTRACT Background There is a need to provide up‐to‐date, clinically translatable data as it relates to the treatment of a major depressive episode (MDE) with mixed features. Methods PubMed and OVID were searched from inception to July 22, 2024. Randomized controlled trials (RCTs) investigating the efficacy of pharmacological agents for adults with ...
Naomi Xiao +12 more
wiley +1 more source
BMC Neuroscience, 2010 Background The molecular and biological mechanisms by which many antidepressants function are based on the monoamine depletion hypothesis. However, the entire cascade of mechanisms responsible for the therapeutic effect of antidepressants has not yet ...
Shin Minkyu +8 more
doaj +1 more source
A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1
ACS Chemical Biology, 2014 Lysine-specific demethylase 1 (LSD1) is an epigenetic enzyme that oxidatively cleaves methyl groups from monomethyl and dimethyl Lys4 of histone H3 (H3K4Me1, H3K4Me2) and can contribute to gene silencing.
P. Prusevich +21 more
semanticscholar +1 more source
Research Trends on Atypical Depression: Based on the Changes in the Number of Articles and the Keywords [PDF]
, 2016 本論文では，非定型うつ病に関する研究の動向を調べ，その背景について検討した．まず，非定型うつ病に関する文献数の推移を概観したところ，非定型うつ病に関する研究が増加傾向にあることが 明らかになった．そして，この推移には，非定型うつ病が DSM で記載されたことが影響を与えてい ると推察された．また，非定型うつ病の定義や診断基準に関する研究の増加も影響を与えていると考 えられた．次に，各文献のキーワードを整理したところ，これまで主に取り上げられてきたキーワー ドは，非定型うつ病や抑うつ障害，双極性障害 ...
保野 孝弘 +4 more
core +1 more source
Manifestation and Measurement of Atypical Depression: A Scoping Review
Clinical Psychology &Psychotherapy, Volume 32, Issue 4, July/August 2025.ABSTRACT Background Atypical depression (AD) is one of the commonly experienced depressive subtypes and is predicted to become more prevalent despite the term ‘atypical’, implying that the condition is rare. Objective This scoping review synthesises the evidence on the manifestation and measurement of AD.
Syeda M. Zahra +5 more
wiley +1 more source
Journal of Oral Rehabilitation, Volume 52, Issue 6, Page 923-936, June 2025.ABSTRACT Background Chronic temporomandibular disorder (TMD) pain significantly impairs quality of life and lacks universally effective treatments. Antidepressants, traditionally used for mood disorders, have shown potential in managing chronic pain conditions.
Takara Dei +5 more
wiley +1 more source
Mat á árangri hugrænnar atferlismeðferðar í hóp við félagsfælni [PDF]
, 2007 Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenÁ geðsviði Landspítala-háskólasjúkrahúss hefur undanfarin ár verið veitt hugræn atferlismeðferð í hóp við félagsfælni.
Brynjar Halldórsson +2 more
core
The effect of placebo and neurophysiological involvements [PDF]
, 2004 Placebo and placebo effect are important issues related to the drug therapy for clinical and scientific meanings. The rates of placebo may get as many as 50% for analgesic drugs in headache. The high answer to placebo brings questions on pathophysiology
Galli, Federica +2 more
core +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 1, March 2025.The case was a 62‐year‐old woman with delusional disorder, somatic type (DDST), presenting with oral somatic delusions. Escitalopram treatment (10 mg/day, increased to 20 mg/day) led to significant symptom improvement, and the symptoms of DDST had nearly resolved approximately 5 weeks after the initiation of escitalopram.
Yunosuke Mizuno +7 more
wiley +1 more source
HIV Medicine, Volume 26, Issue 3, Page 465-478, March 2025.Abstract Introduction Depressive symptoms are highly prevalent among people with HIV, which can negatively impact HIV‐related outcomes. We explore the cascade of mental healthcare for people with HIV experiencing depressive symptoms. Methods People with HIV who were part of the Pharmacokinetic and clinical Observations in PeoPle over fiftY (POPPY ...
Hajra Okhai +12 more
wiley +1 more source