Results 101 to 110 of about 4,826 (188)

Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate [PDF]

Carcinogenesis, 2006
Prostate cancer usually progresses to androgen refractory after an initial anti-androgen treatment. The androgen receptor (AR) is a pivotal factor for the androgen-mediated growth and maintenance of the prostate. Abnormality of the AR, such as overexpression has been postulated to be related to the hormone independent growth of the cancer.
L G, Wang, X M, Liu, J W, Chiao
openaire   +3 more sources

Thiourea‐Based Compounds Effectiveness Against the Growth of Mycobacterium kansasii: Synthesis, Biological Activity, and Computational Analysis

ChemistrySelect, Volume 10, Issue 16, April 25, 2025.
Fifty thiourea derivatives are synthesized and evaluated against Mycobacterium kansasii. Compounds 2, 47, and 49 demonstrate potent extra‐ and intracellular activity without causing macrophage cytotoxicity, even against the hypervirulent strains. Structure–activity relationships and in silico analyses highlight favorable molecular features and predict ...
Sanderson Dias Calixto, Thatiana Lopes Biá Ventura Simão, Marcos V. Palmeira‐Mello, Gil Mendes Viana, Paloma Wetler Meireles Carreiros Assumpção, Dandara Paiva Barroso de Souza, Camila Couto do Espirito Santo, Vinicius de Oliveira Mussi, Carlos Rangel Rodrigues, Alessandra Mendonça Teles de Souza, Bárbara de A. Abrahim‐Vieira, Lúcio Mendes Cabral, Elena Lasunskaia, Michelle Frazão Muzitano   +13 more
wiley   +1 more source

Current status and perspectives of esophageal cancer: a comprehensive review

Cancer Communications, Volume 45, Issue 3, Page 281-331, March 2025.
Abstract Esophageal cancer (EC) continues to be a significant global health concern, with two main subtypes: esophageal squamous cell carcinoma and esophageal adenocarcinoma. Prevention and changes in etiology, improvements in early detection, and refinements in the treatment have led to remarkable progress in the outcomes of EC patients in the past ...
Wei Jiang, Bo Zhang, Jiaqi Xu, Liyan Xue, Luhua Wang   +4 more
wiley   +1 more source

Discrimination Among New Vegetative Materials of Passiflora edulis Sims. From Canary Islands by Their Volatile Profile

Flavour and Fragrance Journal, Volume 40, Issue 2, Page 365-383, March 2025.
The volatile compound profiling of different passion fruit samples grown in the Canary Islands is performed by HS‐SPME‐GC–MS, while applying novel green metrics to show sustainability, and with linear discrimination analysis able to discriminate a new variety. ABSTRACT This study shows the successful discrimination among different passion fruit samples
Montse Saura‐Cayuela, José M. García‐Fraga, Juan Cabrera‐Cabrera, María J. Grajal‐Martín, Juan H. Ayala, María J. Trujillo‐Rodríguez, Verónica Pino   +6 more
wiley   +1 more source

Overexpression of glutathione transferase E7 in Drosophila differentially impacts toxicity of organic isothiocyanates in males and females.

PLoS ONE, 2014
Organic isothiocyanates (ITCs) are allelochemicals produced by plants in order to combat insects and other herbivores. The compounds are toxic electrophiles that can be inactivated and conjugated with intracellular glutathione in reactions catalyzed by ...
Aslam M A Mazari, Olle Dahlberg, Bengt Mannervik, Mattias Mannervik   +3 more
doaj   +1 more source

Allyl-isothiocyanate treatment induces a complex transcriptional reprogramming including heat stress, oxidative stress and plant defence responses in Arabidopsis thaliana [PDF]

, 2016
Comparison of the transcriptional response to allyl-ITC with the CPR response.
Anders Øverby, Atle M. Bones, Per Winge, Ralph Kissen   +3 more
core   +4 more sources

Real‐Time Monitoring of Volatile Organic Compound‐Mediated Plant Intercommunication Using Surface‐Enhanced Raman Scattering Nanosensor

Advanced Science, Volume 12, Issue 7, February 17, 2025.
Living plants are transformed into autonomous sensors for volatile organic compounds (VOCs) by incorporating surface‐enhanced Raman scattering (SERS) nanosensors. This nanobionic sensor allows the plant to monitor VOCs in real‐time, exploiting the plant's inherent ability to communicate.
Yun Sik Choi, Won Ki Son, Hyuna Kwak, Jiyeun Park, Sumin Choi, Daeseob Sim, Min Gyeong Kim, Hyungsuk Kimm, Hokyoung Son, Dae Hong Jeong, Seon‐Yeong Kwak   +10 more
wiley   +1 more source

Isothiocyanates as Novel Cancer Chemopreventive Agents and Their Underlying Molecular Mechanisms [PDF]

, 2006
A promising group of compounds that have a chemopreventive property are isothiocyanates (ITCs). ITCs have been shown to induce apoptosi in various cancer cell lines and experimental rodents.
Nakamura, Yoshimasa
core  

Effect of Caffeic Acid and Chitosan on Spermatological Parameters and Pregnancy Rate in Tuj Breed Ram Semen

Andrologia, Volume 2025, Issue 1, 2025.
The aim of this study is to determine the effect of caffeic acid and chitosan (CS) added to the sperm diluent on post‐thaw spermatological parameters and pregnancy rates in laparoscopic artificial insemination (AI) procedures by utilizing their protective effects.
Taygun Gökdemir, Savaş Yıldız, Shuiqiao Yuan   +2 more
wiley   +1 more source

Cancer prevention by targeting angiogenesis [PDF]

, 2012
Healthy individuals can harbour microscopic tumours and dysplastic foci in different organs in an undetectable and asymptomatic state for many years. These lesions do not progress in the absence of angiogenesis or inflammation.
Albini A, Li V W, Li W W, Noonan D, Tosetti F   +4 more
core   +1 more source