Results 111 to 120 of about 4,826 (188)

Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro

International Journal of Oncology, 2017
Benzyl isothiocyanate (BITC), and phenethyl isothiocyanate (PEITC) have been demonstrated to induce anticancer function in many human cancer cells and also inhibit cancer cell migration and invasion. However, there are no studies that show BITC and PEITC to inhibit cell migration and invasion in mouse melanoma B16F10 cells.
Kuang-Chi, Lai, Yung-Ting, Hsiao, Jiun-Long, Yang, Yi-Shih, Ma, Yi-Ping, Huang, Tai-An, Chiang, Jing-Gung, Chung   +6 more
openaire   +3 more sources

Methods of Modifying the Content of Glucosinolates and Their Derivatives in Sprouts and Microgreens During Their Cultivation and Postharvest Handling

International Journal of Food Science, Volume 2025, Issue 1, 2025.
Sprouts and microgreens which belong to the Brassicaceae family contain significantly more glucosinolates than mature vegetables, and their composition often differs too. These plant growth stages can be a valuable supplement of the aforementioned compounds in the diet.
Magdalena Michalczyk, Mozaniel Oliveira
wiley   +1 more source

Phytochemical Combinations Modulate the Activation of Nrf2 and Expression of SOD in Pancreatic Cancer Cells More Efficiently Than Single Plant Components

Proceedings, 2019
Pancreatic adenocarcinoma mainly occurs in elderly people. Thus, the management of pancreatic cancer in the aging population is becoming increasingly relevant.
Violetta Krajka-Kuźniak, Marta Cykowiak, Wanda Baer-Dubowska   +2 more
doaj   +1 more source

Therapeutic Efficacy of Allyl Isothiocyanate Evaluated on N-Nitrosodiethylamine/Phenobarbitol Induced Hepatocarcinogenesis in Wistar Rats [PDF]

, 2010
N-nitrosodiethylamine (NDEA) is a potential carcinogenic agent that induces liver cancer. To evaluate the chemotherapeutic effect of Allyl isothiocyanate in the experimental model, Wistar male rats were administered single dose of intraperitoneal (IP ...
Gowtham Kumar, A. S., Madhusudhanan, N. (N), Ramakrishnan, V. (V), Selvam, C. A. (C), Thiyagarajan, G. (G)   +4 more
core  

The Role and Applied Value of Mitochondria in Glioma‐Related Research

CNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.
ABSTRACT Mitochondria, known as the “energy factory” of cells, are essential organelles with a double membrane structure and genetic material found in most eukaryotic cells. They play a crucial role in tumorigenesis and development, with alterations in mitochondrial structure and function in tumor cells leading to characteristics such as rapid ...
Liwen Chen, Hui Zhang, Chao Shang, Yang Hong   +3 more
wiley   +1 more source

Phenethyl isothiocyanate inhibits the carcinogenic properties of hepatocellular carcinoma Huh7.5.1 cells by activating MAPK/PI3K-Akt/p53 signaling pathways [PDF]

PeerJ
Background Hepatocellular carcinoma (HCC) is an aggressive malignancy with limited effective treatment options. Phenethyl isothiocyanate (PEITC) is a bioactive substance present primarily in the cruciferous vegetables.
Jiao Du, Yuting Zhang, Jiajia Chen, Libo Jin, Liying Pan, Pengyu Lei, Sue Lin   +6 more
doaj   +2 more sources

Regulation of the mammalian heat shock factor 1 [PDF]

, 2017
Living organisms are endowed with the capability to tackle various forms of cellular stress due to the presence of molecular chaperone machinery complexes that are ubiquitous throughout the cell. During conditions of proteotoxic stress, the transcription
Dayalan Naidu, Sharadha, Dinkova-Kostova, Albena T.   +1 more
core   +2 more sources

In Vitro and In Vivo Inhibition of Human Bladder Cancer by Broccoli Isothiocyanates: Characterization, Absorption, Metabolism and Interconversion [PDF]

, 2011
Biological Sciences: 1st Place (The Ohio State University Edward F. Hayes Graduate Research Forum)Transitional cell carcinoma of the urinary bladder is the fifth most common neoplasm and the twelfth leading cause of cancer death in the United States.
Abbaoui, Besma
core  

Phenethyl Isothiocyanate Inhibits Nasopharyngeal Carcinoma Cell Growth and Invasion [PDF]

Journal of Diseases and Medicinal Plants, 2019
The dietary compound phenethyl isothiocyanate (PEITC), is an active component of cruciferous vegetables and markedly inhibits the growth of a variety of tumors. However, its role in human nasopharyngeal carcinoma (NPC) is obscure. The aim of the present study was to elucidate the possible mechanisms whereby PEITC exhibited anticancer properties in ...
openaire   +1 more source

Watercress and Water Quality: The Effect of Phenethyl Isothiocyanate on the Mating Behaviour of Gammarus pulex

International Journal of Zoology, 2011
Watercress releases phenethyl isothiocyanate (PEITC) upon wounding as a defence against herbivores. PEITC levels released from watercress farms are elevated due to cropping, washing, and processing and are thought to lead to adverse effects on Gammarus ...
Melanie J. Dixon, Peter J. Shaw
doaj   +1 more source