International Journal of Food Science, Volume 2025, Issue 1, 2025.Sprouts and microgreens which belong to the Brassicaceae family contain significantly more glucosinolates than mature vegetables, and their composition often differs too. These plant growth stages can be a valuable supplement of the aforementioned compounds in the diet.
Magdalena Michalczyk, Mozaniel Oliveira
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Isothiocyanates as Novel Cancer Chemopreventive Agents and Their Underlying Molecular Mechanisms [PDF]
, 2006 A promising group of compounds that have a chemopreventive property are isothiocyanates (ITCs). ITCs have been shown to induce apoptosi in various cancer cell lines and experimental rodents.
Nakamura, Yoshimasa
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Regulation of the mammalian heat shock factor 1 [PDF]
, 2017 Living organisms are endowed with the capability to tackle various forms of cellular stress due to the presence of molecular chaperone machinery complexes that are ubiquitous throughout the cell. During conditions of proteotoxic stress, the transcription
Dayalan Naidu, Sharadha +1 more
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The Role and Applied Value of Mitochondria in Glioma‐Related Research
CNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.ABSTRACT Mitochondria, known as the “energy factory” of cells, are essential organelles with a double membrane structure and genetic material found in most eukaryotic cells. They play a crucial role in tumorigenesis and development, with alterations in mitochondrial structure and function in tumor cells leading to characteristics such as rapid ...
Liwen Chen +3 more
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Allyl-isothiocyanate treatment induces a complex transcriptional reprogramming including heat stress, oxidative stress and plant defence responses in Arabidopsis thaliana [PDF]
, 2016 Comparison of the transcriptional response to allyl-ITC with the CPR response.
Anders Øverby +3 more
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Proceedings, 2019 Pancreatic adenocarcinoma mainly occurs in elderly people. Thus, the management of pancreatic cancer in the aging population is becoming increasingly relevant.
Violetta Krajka-Kuźniak +2 more
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Contradictory Role of Gadd45β in Liver Diseases
Journal of Cellular and Molecular Medicine, Volume 28, Issue 23, December 2024.ABSTRACT There are three homologous proteins (α, β and γ) in the growth arrest and DNA damage 45 (Gadd45) family. These proteins act as cellular responders to physiological and environmental stimuli. Gadd45β plays a significant role in the pathogenesis of liver diseases. Liver injury and growth stimulation increase expression of Gadd45β, which promotes
Chi Wu +6 more
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Therapeutic Efficacy of Allyl Isothiocyanate Evaluated on N-Nitrosodiethylamine/Phenobarbitol Induced Hepatocarcinogenesis in Wistar Rats [PDF]
, 2010 N-nitrosodiethylamine (NDEA) is a potential carcinogenic agent that induces liver cancer. To evaluate the chemotherapeutic effect of Allyl isothiocyanate in the experimental model, Wistar male rats were administered single dose of intraperitoneal (IP ...
Gowtham Kumar, A. S. +4 more
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Phenethyl isothiocyanate inhibits the carcinogenic properties of hepatocellular carcinoma Huh7.5.1 cells by activating MAPK/PI3K-Akt/p53 signaling pathways [PDF]
PeerJBackground Hepatocellular carcinoma (HCC) is an aggressive malignancy with limited effective treatment options. Phenethyl isothiocyanate (PEITC) is a bioactive substance present primarily in the cruciferous vegetables.
Jiao Du +6 more
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In Vitro and In Vivo Inhibition of Human Bladder Cancer by Broccoli Isothiocyanates: Characterization, Absorption, Metabolism and Interconversion [PDF]
, 2011 Biological Sciences: 1st Place (The Ohio State University Edward F. Hayes Graduate Research Forum)Transitional cell carcinoma of the urinary bladder is the fifth most common neoplasm and the twelfth leading cause of cancer death in the United States.
Abbaoui, Besma
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