Phenethyl Isothiocyanate Inhibits Nasopharyngeal Carcinoma Cell Growth and Invasion [PDF]
Journal of Diseases and Medicinal Plants, 2019 The dietary compound phenethyl isothiocyanate (PEITC), is an active component of cruciferous vegetables and markedly inhibits the growth of a variety of tumors. However, its role in human nasopharyngeal carcinoma (NPC) is obscure. The aim of the present study was to elucidate the possible mechanisms whereby PEITC exhibited anticancer properties in ...
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Gut Glucosinolate Metabolism and Isothiocyanate Production [PDF]
, 2018 The glucosinolate‐myrosinase system in plants has been well studied over the years while relatively little research has been undertaken on the bacterial metabolism of glucosinolates.
Narbad, Arjan, Trevor Rossiter, John
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BMC Cancer, 2007 Background The development of effective chemopreventive agents against cigarette smoke-induced lung cancer could be greatly facilitated by suitable laboratory animal models, such as animals treated with the tobacco-specific lung carcinogen 4 ...
Xia Dong +6 more
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Aromatic Glucosinolate Biosynthesis Pathway in Barbarea vulgaris and its Response to Plutella xylostella Infestation [PDF]
, 2016 The inducibility of the glucosinolate resistance mechanism is an energy-saving strategy for plants, but whether induction would still be triggered by glucosinolate-tolerant Plutella xylostella (diamondback moth, DBM) after a plant had evolved a new ...
Di Shen +8 more
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Development of Keap1-interactive small molecules that regulate Nrf2 transcriptional activity [PDF]
, 2016 There has been considerable progress recently in the discovery and development of Keap1-interactive compounds that enhance Nrf2 transcriptional activity.
Gatliff, J, Georgakopoulos, ND, Wells, G
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ROS accumulation by PEITC selectively kills ovarian cancer cells via UPR-mediated apoptosis
Frontiers in Oncology, 2015 Unfolded protein response (UPR) is crucial for both survival and death of mammalian cells, which is regulated by reactive oxygen species (ROS) and nutrient depletion.
Yoon-hee eHong +11 more
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Molecules, 2018 Glucosinolates (GSL) are naturally occurring β-d-thioglucosides found across the cruciferous vegetables. Core structure formation and side-chain modifications lead to the synthesis of more than 200 types of GSLs in Brassicaceae.
Prabhakaran Soundararajan, Jung Sun Kim
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Combination of Phenethyl Isothiocyanate and Dasatinib Inhibits Hepatocellular Carcinoma Metastatic Potential through FAK/STAT3/Cadherin Signalling and Reduction of VEGF Secretion. [PDF]
Pharmaceutics, 2023 Strusi G +5 more
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Phenethyl Isothiocyanate-Conjugated Chitosan Oligosaccharide Nanophotosensitizers for Photodynamic Treatment of Human Cancer Cells. [PDF]
Int J Mol Sci, 2022 Bae I +7 more
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