Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1. [PDF]
Mol Nutr Food Res, 2018 Cruciferous vegetables are rich sources of glucosinolates which are the biogenic precursor molecules of isothiocyanates (ITCs). The relationship between the consumption of cruciferous vegetables and chemoprotection has been widely documented in ...
Dayalan Naidu S +4 more
europepmc +8 more sources
A Naturally Derived Watercress Flower-Based Phenethyl Isothiocyanate-Enriched Extract Induces the Activation of Intrinsic Apoptosis via Subcellular Ultrastructural and Ca2+ Efflux Alterations in an In Vitro Model of Human Malignant Melanoma. [PDF]
Nutrients, 2023 Kyriakou S +8 more
europepmc +3 more sources
Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical. [PDF]
PLoS ONE, 2016 Dietary isothiocyanates abundant as glucosinolate precursors in many edible cruciferous vegetables are effective for prevention of cancer in chemically-induced and transgenic rodent models. Some of these agents, including phenethyl isothiocyanate (PEITC),
Vandana Kumari +5 more
doaj +2 more sources
Using Sensors and Generators of H2O2 to Elucidate the Toxicity Mechanism of Piperlongumine and Phenethyl Isothiocyanate. [PDF]
Antioxid Redox Signal, 2016 Aims: Chemotherapeutics target vital functions that ensure survival of cancer cells, including their increased reliance on defense mechanisms against oxidative stress compared to normal cells.
Huang BK, Langford TF, Sikes HD.
europepmc +3 more sources
Designing of the Anticancer Nanocomposite with Sustained Release Properties by Using Graphene Oxide Nanocarrier with Phenethyl Isothiocyanate as Anticancer Agent [PDF]
Pharmaceutics, 2018 In this study anticancer nanocomposite was designed using graphene oxide (GO) as nanocarrier and Phenethyl isothiocyanate (PEITC) as anticancer agent. The designed formulation was characterized in detailed with XRD, Raman, UV/Vis, FTIR, DLS and TEM etc ...
Dasan Mary Jaya Seema +7 more
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DNA methylome, transcriptome, and prostate cancer prevention by phenethyl isothiocyanate in TRAMP mice. [PDF]
Mol Carcinog, 2021 Wu R +9 more
europepmc +3 more sources
p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition [PDF]
Journal of Experimental & Clinical Cancer Research, 2019 Background We reported previously that phenethyl isothiocyanate (PEITC), a dietary compound, can reactivate p53R175H mutant in vitro and in SK-BR-3 (p53R175H) breast xenograft model resulting in tumor inhibition. Because of the diversity of human cancers
Monika Aggarwal +10 more
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PLoS ONE, 2011 Phenethyl isothiocyanate (PEITC) is a promising cancer chemopreventive component of edible cruciferous vegetables with in vivo efficacy against prostate cancer in experimental rodents.
Su-Hyeong Kim +4 more
doaj +2 more sources
Watercress and Water Quality: The Effect of Phenethyl Isothiocyanate on the Mating Behaviour of Gammarus pulex [PDF]
International Journal of Zoology, 2011 Watercress releases phenethyl isothiocyanate (PEITC) upon wounding as a defence against herbivores. PEITC levels released from watercress farms are elevated due to cropping, washing, and processing and are thought to lead to adverse effects on Gammarus ...
Melanie J. Dixon, Peter J. Shaw
doaj +2 more sources
Phenethyl Isothiocyanate and Cisplatin Co-Encapsulated in a Liposomal Nanoparticle for Treatment of Non-Small Cell Lung Cancer [PDF]
Molecules, 2019 Lung cancer is the leading cause of cancer-related death in the Unites States, and approximately 85% of all lung cancers are classified as non-small cell lung cancer (NSCLC), which is extremely difficult to treat and its survival rate is low.
Mengwei Sun +3 more
doaj +2 more sources