p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition [PDF]
Journal of Experimental & Clinical Cancer Research, 2019 Background We reported previously that phenethyl isothiocyanate (PEITC), a dietary compound, can reactivate p53R175H mutant in vitro and in SK-BR-3 (p53R175H) breast xenograft model resulting in tumor inhibition. Because of the diversity of human cancers
Monika Aggarwal +10 more
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Quantitative determination of .BETA.-phenethyl isothiocyanate.
NIPPON SHOKUHIN KOGYO GAKKAISHI, 1985 (1) 溶媒にn-ヘキサンを,内部標準物質にチオナフテンを用いるGCにより,β-フェネチルからし油の定量をこころみた。(2) FIDおよびFPDを用いたGCでは,定温と昇温条件のいずれでも,定量は可能であった。(3) ホース粉加水分解物中には,β-フェネチルからし油含量は,FPD(昇温)を用いるGCでは,0.128～0.241重量%であった。
MISAO KOJIMA +2 more
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Dietary Phenethyl Isothiocyanate Protects Mice from Colitis Associated Colon Cancer. [PDF]
Int J Mol Sci, 2017 We have previously reported alleviation of dextran sodium sulfate (DSS)-induced ulcerative colitis signs in phenethyl isothiocyanate (PEITC)-treated mice. Here we investigated chemoprotective activities of PEITC in mice with Azoxymethane-DSS induced colitis associated colon carcinogenesis.
Liu Y, Dey M.
europepmc +4 more sources
Phenethyl isothiocyanate: a comprehensive review of anti-cancer mechanisms. [PDF]
Biochim Biophys Acta, 2014 The epidemiological evidence suggests a strong inverse relationship between dietary intake of cruciferous vegetables and the incidence of cancer. Among other constituents of cruciferous vegetables, isothiocyanates (ITC) are the main bioactive chemicals present.
Gupta P +3 more
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PLoS ONE, 2011 Phenethyl isothiocyanate (PEITC) is a promising cancer chemopreventive component of edible cruciferous vegetables with in vivo efficacy against prostate cancer in experimental rodents.
Su-Hyeong Kim +4 more
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Watercress and Water Quality: The Effect of Phenethyl Isothiocyanate on the Mating Behaviour of Gammarus pulex [PDF]
International Journal of Zoology, 2011 Watercress releases phenethyl isothiocyanate (PEITC) upon wounding as a defence against herbivores. PEITC levels released from watercress farms are elevated due to cropping, washing, and processing and are thought to lead to adverse effects on Gammarus ...
Melanie J. Dixon, Peter J. Shaw
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Phenethyl Isothiocyanate and Cisplatin Co-Encapsulated in a Liposomal Nanoparticle for Treatment of Non-Small Cell Lung Cancer [PDF]
Molecules, 2019 Lung cancer is the leading cause of cancer-related death in the Unites States, and approximately 85% of all lung cancers are classified as non-small cell lung cancer (NSCLC), which is extremely difficult to treat and its survival rate is low.
Mengwei Sun +3 more
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Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin. [PDF]
Cancers (Basel), 2020 Nguyen YT +3 more
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Dietary Phenethyl Isothiocyanate Alters Gene Expression in Human Breast Cancer Cells [PDF]
Evidence-Based Complementary and Alternative Medicine, 2010 Phenethyl isothiocyanate (PEITC), a component in cruciferous vegetables, can block chemical carcinogenesis in animal models. Our objective was to determine the effect of treatment with PEITC on gene expression changes in MCF‐7 human breast cancer cells in order to evaluate potential mechanisms involved in its chemopreventive effects.
Young Jin Moon +2 more
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Comparison of the Impact of Xanthohumol and Phenethyl Isothiocyanate and Their Combination on Nrf2 and NF-κB Pathways in HepG2 Cells In Vitro and Tumor Burden In Vivo. [PDF]
Nutrients, 2021 Cykowiak M +8 more
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