Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin. [PDF]
Cancers (Basel), 2020 Nguyen YT +3 more
europepmc +3 more sources
Comparison of the Impact of Xanthohumol and Phenethyl Isothiocyanate and Their Combination on Nrf2 and NF-κB Pathways in HepG2 Cells In Vitro and Tumor Burden In Vivo. [PDF]
Nutrients, 2021 Cykowiak M +8 more
europepmc +3 more sources
Haematologica, 2011 Background Isothiocyanates, a family of phytochemicals found in cruciferous vegetables, have cytotoxic effects against several types of tumor cells. Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone ...
Jana Jakubikova +17 more
doaj +3 more sources
Dietary Isothiocyanates, Sulforaphane and 2-Phenethyl Isothiocyanate, Effectively Impair Vibrio cholerae Virulence. [PDF]
Int J Mol Sci, 2021 Vibrio cholerae represents a constant threat to public health, causing widespread infections, especially in developing countries with a significant number of fatalities and serious complications every year. The standard treatment by oral rehydration does not eliminate the source of infection, while increasing antibiotic resistance among pathogenic V ...
Krause K +6 more
europepmc +4 more sources
Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model [PDF]
, 2012 Ovarian cancer is the leading cause of cancer related deaths in women. Genetic alterations including overexpression of EGFR play a crucial role in ovarian carcinogenesis.
Joseph Alan Bauer +4 more
core +13 more sources
Phenethyl Isothiocyanate, a Bioactive Agent for Gastrointestinal Health: A Review [PDF]
, 2021 The incidence of gastrointestinal diseases (cancer in particular) has increased progressively with considerable morbidity, mortality, and a high economic impact on the healthcare system. Dietary intake of natural bioactive phytochemicals showed to have cancer-preventing and therapeutic effects.
Ezequiel R. Coscueta +3 more
openalex +4 more sources
Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells. [PDF]
Pharmacol Res, 2016 Boyanapalli SS +7 more
europepmc +2 more sources
Inhibition of hypoxia inducible factor by phenethyl isothiocyanate [PDF]
Biochemical Pharmacology, 2009 Phenethyl isothiocyanate (PEITC), a natural dietary isothiocyanate, has anti-cancer activity in various in vitro and in vivo models. PEITC inhibits angiogenesis but the molecular mechanisms that underlie this effect are not known. We have now demonstrated that PEITC is an effective inhibitor of hypoxia inducible factor (HIF), a transcription factor ...
Xiuhong Wang +3 more
openalex +6 more sources
Persistence Enhancement of a Promising Tick Repellent, Benzyl Isothiocyanate, by Yeast Microcarriers
Molecules, 2021 Phenethyl isothiocyanate isolated from Armoracia rusticana root oil and its derivatives were tested at different doses in a bioassay designed to evaluate repellency against individual Haemaphysalis longicornis nymphs.
Hui-Ju Kim +3 more
doaj +1 more source
Cells, 2021 Pancreatic cancer is a disease in which deregulation of signaling pathways plays a key role, thus searching for their novel modulators is a promising therapeutic strategy.
Marta Cykowiak +8 more
doaj +1 more source