Results 41 to 50 of about 5,278 (219)
Discover Mental Health, 2022 Mood and anxiety disorders are frequent in the elderly and increase the risk of frailty. This study aimed to identify novel biomarkers of major depressive disorder (MDD) and anxiety in the elderly.
Akiko Fujita +9 more
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Molecules, 2020 Bladder cancer (BC) is a representative of urological cancer with a high recurrence and metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint inhibitors are used as standard therapy in patients with advanced/metastatic BC ...
Tomhiro Mastuo +7 more
doaj +1 more source
Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1. [PDF]
Mol Nutr Food Res, 2018 Cruciferous vegetables are rich sources of glucosinolates which are the biogenic precursor molecules of isothiocyanates (ITCs). The relationship between the consumption of cruciferous vegetables and chemoprotection has been widely documented in ...
Dayalan Naidu S +4 more
europepmc +4 more sources
Using Sensors and Generators of H2O2 to Elucidate the Toxicity Mechanism of Piperlongumine and Phenethyl Isothiocyanate. [PDF]
Antioxid Redox Signal, 2016 Aims: Chemotherapeutics target vital functions that ensure survival of cancer cells, including their increased reliance on defense mechanisms against oxidative stress compared to normal cells.
Huang BK, Langford TF, Sikes HD.
europepmc +3 more sources
Local ciliate communities associated with aquatic macrophytes [PDF]
, 2014 This study, based within the catchment area of the River Frome, an important chalk stream in the south of England, compared ciliated protozoan communities associated with three species of aquatic macrophyte common to lotic habitats: Ranunculus ...
Esteban, Genoveva, Yeates, A.M.
core +4 more sources
Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity
Molecules, 2022 For decades, various plants have been studied as sources of biologically active compounds. Compounds with anticancer and antimicrobial properties are the most frequently desired.
Łukasz Janczewski
doaj +1 more source
Journal of Medical Science, 2014 UDP-glucuronosyltransferases (UGTs) are important detoxification and drug-metabolizing enzymes, which catalyse the glucuronidation of exogenous and endogenous chemicals. The anti-carcinogenic activity of dietary phytochemicals is partly attributed to the
Violetta Krajka-Kuźniak +2 more
doaj +1 more source
Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s) [PDF]
, 2015 ACKNOWLEDGMENTS The work was supported by National Institutes of Health grants DA027113 and EY024717 to G.A.T. and DA09158 to A.M. A portion of this work was submitted in 2011 by A. Kulkarni in partial fulfillment of M.S.
Cascio, Maria G. +12 more
core +3 more sources
Journal of Oral Research, 2022 Introduction: DMBA is a chemical carcinogen that induces carcinomas within a few weeks of its application. We developed an experimental model of carcinogenesis induced by DMBA dissolved in 0,5% paraffin oil (DMBA-PO), verifying the inhibitory effect of ...
María Morales-Herrero +1 more
doaj +1 more source