Drug Delivery, 2023 Rheumatoid arthritis (RA), a systemic autoimmune disease that dramatically affects patients’ quality of life. Given the intricacy of RA’s pathophysiology, no single treatment can completely halt the disease progression.
Prakash Haloi +3 more
doaj +1 more source
MicroRNAs in lung cancer [PDF]
, 2017 Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed countries. Tobacco smoking is considered the main risk factor for LC; however, only a few smokers will be affected by this ...
An +40 more
core +1 more source
New Mild and Simple Approach to Isothiocyanates: A Class of Potent Anticancer Agents
Molecules, 2017 In our current work, acetyl chloride-mediated synthesis of phenethyl isothiocyanate (PEITC) derivatives proves to be convenient and provides the expected products at good to excellent yields.
Bingling Luo +7 more
doaj +1 more source
Supplementary Figure 1 from Atg5 Regulates Phenethyl Isothiocyanate–Induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells [PDF]
, 2023 Ajay Bommareddy +6 more
openalex +2 more sources
Targeting crosstalk between Nrf-2, NF-κB and androgen receptor signaling in prostate cancer [PDF]
, 2018 Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in the initiation, development and progression of prostate cancer (PCa).
Khurana, Namrata, Sikka, Suresh C
core +2 more sources
Asian Pacific Journal of Tropical Medicine, 2018 The National Cancer Institute had projected breast cancer (BC) as one of the topmost prevalent malignancies around the globe. In many cases, BC becomes resistant to chemotherapy, radiation and hormonal therapies.
Banzeer Ahsan Abbasi +7 more
doaj +1 more source
Allyl isothiocyanate inhibits actin mediated intracellular transport in Arabidopsis thaliana. [PDF]
, 2015 Volatile allyl isothiocyanate (AITC) derives from the biodegradation of the glucosinolate sinigrin and has been associated with growth inhibition in several plants, including the model plant Arabidopsis thaliana.
Bones, Atle M. +2 more
core +4 more sources
Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder [PDF]
, 2020 Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the core symptoms and no validated biomarkers for clinical use.
Connors, Susan L. +7 more
core +3 more sources
Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention [PDF]
The AAPS Journal, 2009 Development of cancer is a long-term and multistep process which comprises initiation, progression, and promotion stages of carcinogenesis. Conceivably, it can be targeted and interrupted along these different stages. In this context, many naturally occurring dietary compounds from our daily consumption of fruits and vegetables have been shown to ...
Ka Lung, Cheung, Ah-Ng, Kong
openaire +2 more sources
Biological activity of glucosinolate derived compounds isolated from seed meal of Brassica crops and evaluated as plant and food protection agents [PDF]
, 2007 Glucosinolates are amino acid derived allelochemicals characteristic of plants of the order Capparales. These compounds are present in seeds of agriculturally common Brassica crops in varying quantities depending on the species (ref).
Bellostas, N. +8 more
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