Results 71 to 80 of about 5,278 (219)

Supplementary Figure 1 from Atg5 Regulates Phenethyl Isothiocyanate–Induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells [PDF]

, 2023
Ajay Bommareddy, Eun‐Ryeong Hahm, D. Xiao, Anna A. Powolny, Alfred L. Fisher, Yu Jiang, Shivendra V. Singh   +6 more
openalex   +2 more sources

Phenethyl isothiocyanate enhances adriamycin-induced apoptosis in osteosarcoma cells

Molecular Medicine Reports, 2015
Adriamycin (ADM) is a first‑line agent administered during the therapeutic regimes against osteosarcoma. Clinical administration of ADM produces systemic toxicity and resistance in patients, which restricts its applicability. In the present study the effects of phenethyl isothiocyanate (PEITC) on ADM‑induced apoptosis in osteosarcoma cells was ...
Qie, Fan, Xinli, Zhan, Zengming, Xiao, Chong, Liu   +3 more
openaire   +3 more sources

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu, Liyuan Gao, Liyang Wang, Xueke Wang, Lin Jia, Mengyan Deng, Liming Tang, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao   +10 more
wiley   +1 more source

Biological activity of glucosinolate derived compounds isolated from seed meal of Brassica crops and evaluated as plant and food protection agents [PDF]

, 2007
Glucosinolates are amino acid derived allelochemicals characteristic of plants of the order Capparales. These compounds are present in seeds of agriculturally common Brassica crops in varying quantities depending on the species (ref).
Bellostas, N., Casanova, E., Garcia-Mina, J.M., Hansen, L.M., Jørgensen, L.N., Kudsk, P., Madsen, P.H., Sørensen, H., Sørensen, J.C.   +8 more
core  

Cloning and Characterization of a Biotic-Stress-Inducible Glutathione Transferase from Phaseolus vulgaris [PDF]

, 2013
Glutathione transferases (GSTs, EC 2.5.1.18) are ubiquitous proteins in plants that play important roles in stress tolerance and in the detoxification of toxic chemicals and metabolites.
Chronopoulou, Evangelia, Labrou, Nikolaos E., Madesis, Panagiotis, Tsaftaris, Athanasios   +3 more
core   +1 more source

Progress in Surface‐Enhanced Raman Scattering‐Based Volatile Organic Compounds Detection: Materials, Application, and Prospects

Rare Metals, EarlyView.
ABSTRACT The detection of volatile organic compounds (VOCs) holds significant implications in environmental monitoring and disease diagnosis. Traditional gas detection technologies are constrained by complex operation and high cost, thereby failing to satisfy real‐time detection demands.
Yuening Wang, Lin Qiu, Jian Yu, Wen Ma, Xiaoyu Song, Mingjian Zhang, Yujiao Xie, Aochi Liu, Li Sun, Xiangyu Meng, Jie Lin, Xiaotian Wang   +11 more
wiley   +1 more source

Antibacterial activity and mode of action of selected glucosinolate hydrolysis products against bacterial pathogens [PDF]

, 2015
Plants contain numerous components that are important sources of new bioactive molecules with antimicrobial properties. Isothiocyanates (ITCs) are plant secondary metabolites found in cruciferous vegetables that are arising as promising antimicrobial ...
A Aires, A Aires, A Borges, A Borges, A Borges, A Borges, A Conrad, A Rahman, A Sofrata, A Tabata, AA Al-Gendy, AC Abreu, AC Abreu, AD Russell, AD Russell, B Holst, B Janczuk, B Sun, BA Halkier, BA Halkier, BJ McCabe-Sellers, BK Tiwari, C Ferreira, C Jacob, C Wu, CD Grubb, CF Carson, CJ Oss van, CJ Oss van, CJ Oss van, CM Lin, CM Lin, CM Park, E Hong, EFSA, ES Ahn, F Ahimou, F Mushantaf, FB Luciano, FB Luciano, G Barbieri, G Lerebour, G Tegos, H Chen, H Tajima, HJ Busscher, IS Shin, J Heidler, J Palmer, JL Dangl, JW Fahey, K Cejpek, KH Kyung, L Tang, LF D’Antuono, M Cartea, M Jang, M Oussalah, M Saleem, M Simões, M Simões, M Simões, M Simões, MG Kim, MJ Saavedra, MM Cowan, MP Bos, MS Rhee, MT Black, NG Chorianopoulos, P Gilbert, PA Lambert, PJ Delaquis, PS Negi, R Munday, R Troncoso, RA Dixon, RH Kolm, RN Jones, RP Verma, S Ananou, S Burt, S Langsrud, SD Sarker, SG Gómez De Saravia, SY Wang, T Zsolnai, T-T Liu, V Dufour, Y Diab, Y Zhang, Y-H Pang   +91 more
core   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Taste and flavour perceptions of glucosinolates, isothiocyanates, and related compounds [PDF]

, 2018
Brassicaceae plants are renowned for their taste, aroma and trigeminal characteristics; predominantly bitter taste, sulfurous aroma and pungency. Compounds responsible for these sensations include the glucosinolates (GSLs) and their hydrolysis products ...
Abe, Agerbirk, Agneta, Agrawal, Baik, Beaver, Behrens, Bell, Bell, Bell, Bell, Bell, Bennett, Bennett, Bonnema, Buck, Cartea, Cerny, Chen, Chin, Chin, Coogan, D'Antuono, D'Auria, Depree, Dinkova-Kostova, Doorn, Drewnowski, Elmore, Elmore, Engel, Fahey, Fenwick, Fenwick, Fowke, Frandsen, Frank, Freeman, Fukuda, Ghawi, Ghawi, Giacoppo, Halkier, Hanschen, Hanschen, Hansen, Hansen, Hasin, Hayes, Hayes, Holst, Hufnagel, Ishida, Jaeger, Jakubikova, Jin, Jirovetz, Jones, Jordt, Kato, Keller, Khataan, Kim, Kirimura, Kubec, Kuchernig, Levine, Lindsay, Ludikhuyze, Matusheski, Matusheski, McRae, Melchini, Mennella, Methven, Meyerhof, Nishimura, Okunade, Padilla, Palaniswamy, Palermo, Park, Parker, Pasini, Pence, Possenti, Prescott, Raffo, Rangkadilok, Reed, Ridgway, Sandell, Sansom, Sarkar, Schonhof, Shapiro, Shen, Siegmund, Steinmetz, Stoewsand, Sultana, Sultana, Suzuki, Swanston, Traka, Traka, Voutsina, Wills, Wold, Wu, Zabaras, Zhao   +111 more
core   +1 more source

Cholesterol‐Lowering and Radical Scavenging Potential of Fermented Black Kale (Brassica oleracea var. acephala): From Pilot‐Scale Production to in Vivo Study

ChemFoodChem, Volume 1, Issue 2, December 1, 2025.
Abstract Vegetables are rich in bioactive compounds, including fibers and minerals, providing a conspicuous contribution to achieving health benefits. In this study, black kale (Brassica oleracea var. acephala, BK) was fermented using Saccharomyces cerevisiae LI180‐7 strain at pilot scale, producing a safe and consumable product featured by improved ...
Mirco Vacca, Annamaria Tarantini, Mohamad Khalil, Danilo Vona, Francesco M. Calabrese, Giuseppe Celano, Carmen A. Apa, Matteo Bernardi, Leonardo Mancini, Gianni Pietragalla, Laura Mahdi, Domenico Rubino, Matteo Spagnuolo, Gianluca Bleve, Piero Portincasa, Maria De Angelis   +15 more
wiley   +1 more source