Results 121 to 130 of about 3,344 (169)
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Effects of Phenformin and PhenforminâEthanol Synergism on the Perfused Rat Liver
Acta Pharmacologica et Toxicologica, 1974Abstract:The metabolic effects of phenformin and phenforminâethanol were studied in isolated perfused liver preparations from fed rats. Whether phenformin was given alone or together with ethanol, the hepatic oxygen consumption decreased and the lactate production increased. Phenformin caused a decrease in ethanol elimination.
C, Olsen, N, Krarup
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Phenformin-associated metabolic acidosis
Diabetes, 1976We report 18 consecutive phenformin-treated diabetic patients admitted to this Medical Service acutely ill with metabolic acidosis. Lactic acidosis was anticipated, and documented, in all. Also, however, though most of the patients had only weakly positive, or even negative, serum reactions with the nitroprusside reagent, all were found to have ...
M, Fulop, H D, Hoberman
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Annals of Internal Medicine, 1977
Excerpt To the editor: We wish to report our experience with a patient who developed pancreatitis while using phenformin.
LAWRENCE M. RYAN +2 more
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Excerpt To the editor: We wish to report our experience with a patient who developed pancreatitis while using phenformin.
LAWRENCE M. RYAN +2 more
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Phenformin Treatment of Diabetes
JAMA: The Journal of the American Medical Association, 1971The AMA Council on Drugs has reviewed a preliminary report of the University Group Diabetes Program (UGDP) study of phenformin as treatment of asymptomatic diabetes. The report appears elsewhere in this issue ofThe Journal(p 777). The Council concludes that the UGDP has produced no data indicating that therapy directed toward lowering the blood ...
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Attempted Suicide with Phenformin
Diabetes, 1965Following ingestion of .85 gm. of phenformin, in a suicide attempt, the principal symptoms were violent gastrointestinal cramping, nausea, and vomiting, all of a few hours' duration. This appeared to provide major protection against other toxic effects. There was no significant hematemesis or melena.
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Effect of Phenformin in Hyperglycemic Rats
Diabetes, 1974Phenformin administered intraperitoneally in doses of 30 and 100 mg. per kilogram significantly reduced the blood glucose concentration in streptozotocin-diabetic rats, but was virtually inactive in normal healthy rats. Phenformin also antagonized the hyperglycemic effect of an intravenous infusion of epinephrine in normal anesthetized rats and ...
I, Polacek, J, Ouart
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