Results 111 to 120 of about 6,979 (257)

The antitumor properties of metformin and phenformin reflect their ability to inhibit the actions of differentiated embryo chondrocyte 1

Cancer Management and Research, 2019
Chun-Lin Kuo,1 Shu-Man Hsieh Li,*,2 Shu-Yi Liang,*,2 Shu-Ting Liu,2 Li-Chun Huang,2 Wei-Ming Wang,3 Li-Chen Yen,2,4 Shih-Ming Huang21Department of Orthopaedic Surgery, Tri-Service General Hospital, National Defense Medical Center, Taiwan ...
Kuo CL, Hsieh Li SM, Liang SY, Liu ST, Huang LC, Wang WM, Yen LC, Huang SM   +7 more
doaj  

Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study

Acta Pharmaceutica, 2018
Extensive in vitro studies have been conducted to evaluate the anticancer activity of oral hypoglycemic agents. Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media ...
Bardaweel Sanaa K., Alsalamat Husam A., Aleidi Shereen M., Bashatwah Rasha M.   +3 more
doaj   +1 more source

Predicting drug response of tumors from integrated genomic profiles by deep neural networks

, 2018
The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response.
Chen, Hung-I Harry, Chen, Yidong, Chiu, Yu-Chiao, Gorthi, Aparna, Huang, Yufei, Wang, Li-Ju, Zhang, Songyao, Zhang, Tinghe   +7 more
core   +1 more source

Alcohol and phenformin in diabetes. [PDF]

, 1970
P Isaacs
openalex   +1 more source

Supplementary Figure 3 from Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib

, 2023
Paul B. Chapman, Mark Klang, Michael A. Postow, Alexander N. Shoushtari, Ryan J. Sullivan, Jedd D. Wolchok, Taha Merghoub, Sadna Budhu, Phillip Wong, Margaret K. Callahan, Bin Zheng, Jonathan H. Zippin   +11 more
openalex   +1 more source

Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment

Drug Design, Development and Therapy, 2014
Kosuke Narise, Kensuke Okuda, Yukihiro Enomoto, Tasuku Hirayama, Hideko Nagasawa Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University, Daigaku-nishi, Gifu, Japan Abstract: Adaptive cellular responses resulting from ...
Narise K, Okuda K, Enomoto Y, Hirayama T, Nagasawa H   +4 more
doaj  

TABLE 2 from Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib

, 2023
Paul B. Chapman, Mark Klang, Michael A. Postow, Alexander N. Shoushtari, Ryan J. Sullivan, Jedd D. Wolchok, Taha Merghoub, Sadna Budhu, Phillip Wong, Margaret K. Callahan, Bin Zheng, Jonathan H. Zippin   +11 more
openalex   +1 more source

Supplementary Figure S3 from Genetic Disruption of Lactate/H⁺ Symporters (MCTs) and Their Subunit CD147/BASIGIN Sensitizes Glycolytic Tumor Cells to Phenformin

, 2023
Ibtissam Marchiq, Renaud Le Floch, Danièle Roux, Marie‐Pierre Simon, Jacques Pouysségur   +4 more
openalex   +2 more sources

Problems in the Insulin Dependent Diabetic [PDF]

, 1966
It is often useful for the physician to classify diabetes as stable or unstable. Maturity-onset diabetes is usually stable, and its management is not difficult, provided the patient is interested and cooperative.
Gardner, Clay T., Jr.
core   +1 more source

Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma

, 2016
Wei Jiang, Susan Finniss, Simona Cazacu, Cunli Xiang, Ziv Brodie, Tom Mikkelsen, Laila Poisson, David B. Shackelford, Chaya Brodie   +8 more
openalex   +2 more sources