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INVESTIGATING APOPTOSIS AS A POTENTIAL PATHWAY FOR ANTICANCER MECHANISM OF PHENFORMIN
Apoptosis is an essential cellular process that maintains cellular homeostasis. Dysregulation of apoptosis can lead to uncontrolled cell proliferation, which may result in the development of cancer. Targeting apoptosis has emerged as a promising strategy
Amangelsin, Yernar
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Purpose: Hepatocellular carcinoma (HCC) ranks second in cancer mortality and has limited therapeutic options. We recently described the synergistic effect of allosteric and ATP-site competitive inhibitors against the mTOR for the treatment of HCC ...
Zorzano Olarte, Antonio +9 more
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Improved pH-Responsive Release of Phenformin from Low-Defect Graphene Compared to Graphene Oxide
ACS Omega, 2021 Abdelnour Alhourani +4 more
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INVESTIGATING AUTOPHAGY AS A POTENTIAL PATHWAY OF ANTICANCER MECHANISM OF PHENFORMIN
Phenformin, a representative of the biguanides class, is an anti-diabetic drug that was withdrawn from the market due to its side effects profile is currently being investigated as a potential anticancer agent.
Khikhmetova, Kamila
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Annals of Internal Medicine, 1973
Excerpt To the editor: The letter by Dr. Wilde (1), which raises the question of a causal association of phenformin and pancreatitis, prompts me to report a case of pancreatitis in association with...
E, Coodley, J, Derasse, J, Carver
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Excerpt To the editor: The letter by Dr. Wilde (1), which raises the question of a causal association of phenformin and pancreatitis, prompts me to report a case of pancreatitis in association with...
E, Coodley, J, Derasse, J, Carver
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Annals of Internal Medicine, 1972
Excerpt To the editor: Phenformin therapy may be associated with a metallic taste, anorexia, nausea, and occasional diarrhea with abdominal cramps.
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Excerpt To the editor: Phenformin therapy may be associated with a metallic taste, anorexia, nausea, and occasional diarrhea with abdominal cramps.
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Phenformin-Associated Lactic Acidosis Due to Imported Phenformin
Diabetes Care, 1996OBJECTIVE To emphasize the continued incidence of phenformin-associated lactic acidosis. CASE REPORT We report a case of phenformin-associated lactic acidosis in a Chinese man who received phenformin while in China.
H C, Lu, P P, Parikh, D L, Lorber
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