Results 141 to 150 of about 78,657 (383)

Role of eIF4A1 in triple‐negative breast cancer stem‐like cell‐mediated drug resistance

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract In cap‐dependent translation, the eukaryotic translation initiation factor 4A (eIF4A1) is an mRNA helicase is involved in unwinding of the secondary structure, such as the stem‐loops, at the 5′‐leader regions of the key oncogenic mRNAs. This facilitates ribosomal scanning and translation of the oncogenic mRNAs.
Dayanidhi Raman, Amit K. Tiwari
wiley   +1 more source

Phenobarbital compared with phenytoin for the treatment of neonatal seizures.

New England Journal of Medicine, 1999
BACKGROUND Seizures occur in 1 to 2 percent of neonates admitted to an intensive care unit. The treatment is usually with either phenobarbital or phenytoin, but the efficacy of the two drugs has not been compared directly. METHODS From 1990 to 1995, we
M. Painter, M. Scher, Aryeh D. Stein, Stacey Armatti, Zhiming Wang, Joseph C. Gardiner, N. Paneth, Beth Minnigh, J. Alvin   +8 more
semanticscholar   +1 more source

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

Advanced Science, EarlyView.
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

ON THE RELATIONSHIP OF LIVER GLUCOSE-6-PHOSPHATASE TO THE PROLIFERATION OF ENDOPLASMIC RETICULUM IN PHENOBARBITAL INDUCTION [PDF]

, 1966
Sten Orrenius, Jan L. E. Ericsson
openalex   +1 more source

Effects of Prenatal Exposure to Phenobarbital on Verbal Abilities in School-Aged Children [PDF]

, 2020
Phenobarbital is one of the oldest medications used for the treatment of epilepsy. Although its use has declined in many developed nations, phenobarbital is still a first-line treatment in several developing countries across the globe.
Lutes, Jocelyn M.
core   +1 more source

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

Advanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang, Zhiyuan Zheng, Shilu Zhu, Liang Xu, Qingdong Zhang, Jie Gao, Min Ye, Shuwei Shen, Jinyu Xing, Ming Wu, Ronald X. Xu   +10 more
wiley   +1 more source

Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development

Advanced Science, EarlyView.
Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He, Mengtian Zhang, Jie Qin, Yanyan Wang, Sihan Li, Chaoyi Du, Jianwei Jiao, Fen Ji   +7 more
wiley   +1 more source

A novel UGT1A1 gene mutation causing severe unconjugated hyperbilirubinemia: a case report

BMC Pediatrics, 2019
Background Crigler-Najjar syndrome (CNs) presents as unconjugated hyperbilirubinemia, as a result of UGT1A1 deficiency, and can be categorized in a severe (type I) and mild (type II) phenotype.
Xiaoxia Shi, Sem Aronson, Ahmed Sharif Khan, Piter J. Bosma   +3 more
doaj   +1 more source

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

Advanced Science, EarlyView.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong, Jin Jiang, Muhammad Hussain, Haoxuan Zhang, Ling Chen, Rongfa Guan   +5 more
wiley   +1 more source

Implementing microwell slides for detection and isolation of single circulating tumor cells from complex cell suspensions

Cytometry Part A, Volume 101, Issue 12, Page 1057-1067, December 2022., 2022
Abstract Cell loss during detection and isolation of circulating tumor cells (CTCs) is a challenge especially when label‐free pre‐enrichment technologies are used without the aid of magnetic particles. Although microfluidic systems can remove the majority of “contaminating” white blood cells (WBCs), their remaining numbers are still impeding single CTC
Liwen Yang, Mahdi Rivandi, André Franken, Maarten Hieltjes, Pieter Jan van der Zaag, Constantin Nelep, Jens Eberhardt, Stefan Peter, Dieter Niederacher, Tanja Fehm, Hans Neubauer   +10 more
wiley   +1 more source