Results 181 to 190 of about 86,047 (385)

Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB Signaling

Advanced Science, EarlyView.
This study identifies that RBM10 represses the transcriptional activity of RORB in liquid condensates, resulting in down‐regulation of NR1D1 and RIOK3 that further activates NF‐κB activity to facilitate lysosomal biogenesis and aggressive features of NB cells.
Yanhua Guo, Xiaojing Wang, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Jiaying Qu, Shunchen Zhou, Liduan Zheng, Qiangsong Tong   +9 more
wiley   +1 more source

Effects of Phenobarbital on the Synthesis and Degradation of the Protein Components of Rat Liver Microsomal Membranes

, 1969
Yoshiaki Kuriyama, T Omura, Philip Siekevitz, George E. Palade   +3 more
openalex   +1 more source

261 RAPID CONTROL OF NEONATAL NARCOTIC ABSTINENCE UTILIZING A PHENOBARBITAL LOADING DOSE METHOD [PDF]

, 1978
Thomas F Mitros, Leigh E. Hopkins, Loretta P. Finnegan   +2 more
openalex   +1 more source

The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice

Epilepsia, 2016
T. Erker, C. Brandt, Kathrin Töllner, Philipp Schreppel, Friederike Twele, Alina Schidlitzki, W. Löscher   +6 more
semanticscholar   +1 more source

Mechanical Cues Regulate Cargo Sorting and Export at the Golgi

Advanced Science, EarlyView.
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino, Stefania Forciniti, Edoardo Scarpa, Antonio Ranieri, Lucia Santorelli, Gabriella De Blasi, Sara Costantini, Eunjoo Jun Lee, Antonio Galeone, Alessia Calcagnì, Marinella Pirozzi, Loretta L. del Mercato, Rossella Venditti, Giovanni D'Angelo, Seetharaman Parashuraman, Tiziano Verri, Giuseppe Gigli, Elizabeth S. Sztul, Paolo Grumati, Loris Rizzello, Domenico Russo, Riccardo Rizzo   +21 more
wiley   +1 more source

Assessing risk of respiratory depression following initial phenobarbital loading for severe alcohol withdrawal syndrome. [PDF]

Crit Care
Suhotliv A, Miller A, Singh J, Torres-Lockhart K, Carriel MS, Mohamed A, Fein DG, Moskowitz A, Blinder V.   +8 more
europepmc   +1 more source

EFFECT OF PHENOBARBITAL ON THE ACTIVITIES OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM OF LIVER MICROSOMES IN ALLOXAN DIABETES AND THYROXINE TREATED RATS

, 1969
Ryuichi Kato, Atsushi Takahashi
openalex   +1 more source

The comparative effects of barbituric acid and phenobarbital on blood glucose and insulin secretion in mice [PDF]

, 1976
John H. Mennear, C. Schonwalder, E. T. Yau   +2 more
openalex   +1 more source

Association of HLA genotypes with phenobarbital hypersensitivity in children

Epilepsia, 2016
Wiparat Manuyakorn, S. Mahasirimongkol, Plernpit Likkasittipan, Wasu Kamchaisatian, S. Wattanapokayakit, W. Inunchot, A. Visudtibhan, N. Wichukchinda, S. Benjaponpitak   +8 more
semanticscholar   +1 more source

Development of a 3D Human Colon Model Along with Bioelectronics for the Induction and Monitoring of Diseases

Advanced Science, EarlyView.
We present a functional three‐dimensional in‐vivo‐mimicking human colon (3D‐IVM‐HC) model engineered via Freeform Reversible Embedding of Suspended Hydrogels bioprinting with gelatin methacrylate (GelMA)/alginate hydrogels. This 3D non‐animal model replicates crypt‐like architectures, epithelial polarization, and stromal–tumor interactions, showing ...
Jorge Alfonso Tavares‐Negrete, Sahar Najafikoshnoo, Anita Ghandehari, Mozhgan Keshavarz, Quinton Smith, Armand Ahmetaj, Steven Zanganeh, Rahim Esfandyarpour   +7 more
wiley   +1 more source