Results 71 to 80 of about 34,408 (289)

Ganaxolone versus Phenobarbital for Neonatal Seizure Management

open access: yes, 2022
OBJECTIVE: Seizures are more common in the neonatal period than at any other stage of life. Phenobarbital is the first-line treatment for neonatal seizures and is at best effective in approximately 50% of babies, but may contribute to neuronal injury ...
Nitsos, I   +17 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Phenobarbital Metabolism in Ethanol-Intoxicated Rats

open access: yes, 1973
The effects of an acute dose of ethanol on the metabolism of 14C-phenobarbital was studied in the rat. The ethanol-treated rats had higher blood and tissue levels of radioactivity than control animals for 10–12 h following oral administration of the ...
C. J. Paul, B. B. Coldwell, B. H. Thomas
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial

open access: yes, 2007
Objective: To compare the behavioural side effects associated with two commonly used antiepilepsy drugs--phenobarbital and carbamazepine--in children in Bangladesh. Design: Prospective randomised controlled single centre trial.
Neville, B.   +5 more
core  

Brain Phenobarbital Uptake during Prolonged Status Epilepticus

open access: yes, 1987
The brain uptake of phenobarbital during prolonged status epilepticus (3 h) was studied in paralyzed, ventilated sheep. The first 30 min of status epilepticus was characterized by systemic hypertension, increased CBF, increased peripheral vascular ...
Neal L. Benowitz   +4 more
core   +1 more source

Influence of phenobarbital and bucolome on biliary bilirubin [PDF]

open access: yes, 1977
Biliary bilirubin conjugates were investigated in heterozygote Gunn rat after loading of phenobarbital or bucolome for 4 days. 50mg of phenobarbital or 200mg of bucolome per Kg of body weight was given intramusculary once a day.
Kondo, Tadasuke   +5 more
core   +1 more source

A Patch Test Confirmed Phenobarbital-Induced Fixed Drug Eruption in a Child

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2014
A-10-year-old girl was referred to our department for multiple hyperpigmented plaques. One  week  previously,  she  had  been  given  one  suppository  of  acetylsalicylic acid  – phenobarbital for fever.
Zohra Chadly   +5 more
doaj  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Toxic epidermal necrolysis caused by phenobarbital: a case report and literature review

open access: yesFrontiers in Pharmacology
BackgroundToxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare, life-threatening immunologic reactions. Previous relevant literature has provided limited information regarding this disease’s genetic susceptibility and management ...
Jie Cheng   +7 more
doaj   +1 more source

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