Results 271 to 280 of about 366,479 (341)

How far have plasticizers and additives penetrated our aquatic environment? [PDF]

open access: yes, 2017
Demeestere, Kristof   +4 more
core  

Palladium‐Catalyzed Aryloxycarbonylayion of Aryl Bromides with Phenols Using Inositol Hexaformate as an Efficient CO Source

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
We designed a novel carbon monoxide surrogate inositol hexaformate (HFI) and applied it to the palladium‐catalyzed aryloxycarbonylation of aryl bromides with phenols. HFI liberates six molecules of carbon monoxide, exhibiting a significantly higher efficiency and CO capacity than the conventional formate surrogates.
Zhen‐Wei Liu   +2 more
wiley   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

open access: yesAdvanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

open access: yesAdvanced Theory and Simulations, EarlyView.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer   +7 more
wiley   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong   +11 more
wiley   +1 more source

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