Results 81 to 90 of about 1,778,805 (292)

THE INTERACTIVITY OF VIRTUAL LANGUAGE CLASS IN INDONESIA (A PHENOMENOLOGICAL STUDY) [PDF]

open access: yesЕзиков свят
Inspired by lecturers’ experience of Emergency Remote Teaching (ERT) during the COVID-19 pandemic, this phenomenological study presents an attempt at producing recommendations for the future construction of virtual language classes in Indonesia.
Nurhasanah Halim   +2 more
doaj   +1 more source

Multiscale phenomena: Green's functions, the Dirichlet-to-Neumann formulation, subgrid scale models, bubbles and the origins of stabilized methods

open access: yes, 1995
An approach is developed for deriving variational methods capable of representing multiscale phenomena. The ideas are first illustrated on the exterior problem for the Helmholtz equation.
T. Hughes
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

The Explanation of Second Analogy (Principle of Causality) in Critique of Pure Reason [PDF]

open access: yesحکمت اسرا, 2014
Kant's attention to the causality is due to conflicts of processes of objectification in subjective concept of causality. The question has always been along the doubts of philosophers in modern era about the duality of body and soul. Philosophers such as
mohammadhadi hazeri   +1 more
doaj  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Constructivist Realism: An Ontology That Encompasses Positivist and Constructivist Approaches to the Social Sciences

open access: yesForum: Qualitative Social Research, 2001
It has been argued that positivist and constructivist ontologies are irreconcilable. According to LINCOLN and GUBA (2000), positivism's "naive realism" holds that reality is both "real" and "apprehendable," whereas constructivism maintains that meaning ...
Gerald Cupchik
doaj  

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