Results 121 to 130 of about 2,808,934 (339)

In vivo spectroscopy and NMR metabolite fingerprinting approaches to connect the dynamics of photosynthetic and metabolic phenotypes in resurrection plant Haberlea rhodopensis during desiccation and recovery

open access: yesFrontiers in Plant Science, 2015
The resurrection plant Haberlea rhodopensis was used to study dynamics of drought response of photosynthetic machinery parallel with changes in primary metabolism.
Petko eMladenov   +14 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A mutation of the Col2a1 gene (G1170S) alters the transgenic murine phenotype and cartilage matrix homeostasis

open access: yesJournal of the Formosan Medical Association, 2014
Genomic studies have revealed that there is a significant association between a point mutation of the human Col2A1 gene (G1170S) and several hip disorders.
Ruei-Cheng Yang   +6 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Quantitative population-epigenetics in screening and development of regulator-active compounds

open access: yesJulius-Kühn-Archiv, 2012
Quantitative (Population-) Epigenetics describes the variability observed in characters due to factors in the environment induced primarily by the gamut of chemical compounds screened for regulatory efficacy.
Stauß, Reinhold
doaj   +1 more source

Phenotype annotation with the ontology of microbial phenotypes (OMP)

open access: yesJournal of Biomedical Semantics, 2019
Microbial genetics has formed a foundation for understanding many aspects of biology. Systematic annotation that supports computational data mining should reveal further insights for microbes, microbiomes, and conserved functions beyond microbes. The Ontology of Microbial Phenotypes (OMP) was created to support such annotation.We define standards for ...
Deborah A. Siegele   +6 more
openaire   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Characterization of Botrytis cinerea populations associated with treated and untreated cv. Moscato vineyards

open access: yesPhytopathologia Mediterranea, 2014
Three Botrytis cinerea populations, isolated from three vineyards, one untreated and two treated twice a year, respectively, with fenhexamid or cyprodinil+fludioxonil, were investigated to evaluate the effect of repeated fungicide treatments on the ...
Annamaria VERCESI   +4 more
doaj   +1 more source

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