Results 21 to 30 of about 605,923 (256)

Lamin A/C Mechanosensor Drives Tumor Cell Aggressiveness and Adhesion on Substrates With Tissue-Specific Elasticity

open access: yesFrontiers in Cell and Developmental Biology, 2021
Besides its structural properties in the nucleoskeleton, Lamin A/C is a mechanosensor protein involved in perceiving the elasticity of the extracellular matrix.
Enrica Urciuoli   +3 more
doaj   +1 more source

Nasopharyngeal microbiota in hospitalized children with Bordetella pertussis and Rhinovirus infection

open access: yesScientific Reports, 2021
Despite great advances in describing Bordetella pertussis infection, the role of the host microbiota in pertussis pathogenesis remains unexplored. Indeed, the microbiota plays important role in defending against bacterial and viral respiratory infections.
A. E. Tozzi   +13 more
doaj   +1 more source

Spike protein is a key target for stronger and more persistent T-cell responses—a study of mild and asymptomatic SARS-CoV-2 infection

open access: yesInternational Journal of Infectious Diseases, 2023
Objectives: Understanding the immune response in very mild and asymptomatic COVID-19 is crucial for developing effective vaccines and immunotherapies, yet remains poorly characterized.
Ivan Ssali   +20 more
doaj   +1 more source

Rapid, early, and potent Spike-directed IgG, IgM, and IgA distinguish asymptomatic from mildly symptomatic COVID-19 in Uganda, with IgG persisting for 28 months

open access: yesFrontiers in Immunology, 2023
IntroductionUnderstanding how spike (S)-, nucleoprotein (N)-, and RBD-directed antibody responses evolved in mild and asymptomatic COVID-19 in Africa and their interactions with SARS-CoV-2 might inform development of targeted treatments and vaccines ...
Jennifer Serwanga   +31 more
doaj   +1 more source

A Novel Microwave Resonant Sensor for Measuring Cancer Cell Line Aggressiveness

open access: yesSensors, 2022
The measurement of biological tissues’ dielectric properties plays a crucial role in determining the state of health, and recent studies have reported microwave biosensing to be an innovative method with great potential in this field.
Livio D’Alvia   +6 more
doaj   +1 more source

Phenotype of Chronic Obstructive Pulmonary Disease Based on Computed Tomography–Defined Underlying Pathology [PDF]

open access: yesTuberculosis and Respiratory Diseases, 2022
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease. Not all patients with COPD respond to available drugs. Identifying respondents to therapy is critical to delivering the most appropriate treatment and avoiding ...
Won-Dong Kim
doaj   +1 more source

Breastfeeding and Respiratory Infections in the First 6 Months of Life: A Case Control Study

open access: yesFrontiers in Pediatrics, 2019
Background: Viral respiratory tract infections (VRI) are a major reason for hospitalization in children younger than 5 years. A case control study was conducted to investigate the potential role of breastfeeding in protecting children <1 year of age ...
Elisabetta Pandolfi   +10 more
doaj   +1 more source

The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data. [PDF]

open access: yes, 2013
The Human Phenotype Ontology (HPO) project, available at http://www.human-phenotype-ontology.org, provides a structured, comprehensive and well-defined set of 10,088 classes (terms) describing human phenotypic abnormalities and 13,326 subclass relations ...
Smith, C.L.   +200 more
core   +2 more sources

Phenotypic and genotypic characteristics of children with Bartter syndrome

open access: yesThe Turkish Journal of Pediatrics, 2022
Introduction. Bartter syndrome (BS) is a group of autosomal-recessive tubular disorders and it is classified into five genetic subtypes. BS can also be classified by phenotype (antenatal, classic).
Serçin Güven   +10 more
doaj   +1 more source

Clinical and genetic analysis of 29 Brazilian patients with Huntington’s disease-like phenotype [PDF]

open access: yes, 2011
Huntington’s disease (HD) is a neurodegenerative disorder characterized by chorea, behavioral disturbances and dementia, caused by a pathological expansion of the CAG trinucleotide in the HTT gene. Several patients have been recognized with the typical
Lopes-Cendes, Iscia   +31 more
core   +1 more source

Home - About - Disclaimer - Privacy