Results 41 to 50 of about 2,761,247 (301)

Measuring phenotype-phenotype similarity through the interactome [PDF]

2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2017
Recently, measuring phenotype similarity began to play an important role in disease diagnosis. Researchers have begun to pay attention to develop phenotype similarity measurement. However, existing methods ignore the interactions between phenotype-associated proteins, which may lead to inaccurate phenotype similarity.We proposed a network-based method ...
Jiajie Peng, Weiwei Hui, Xuequn Shang
openaire   +4 more sources

Treating Macrophages with Anti-inflammatory Nanoparticles as a Strategy to Improve Muscle Repair [PDF]

, 2019
The macrophage is an immune cell that is involved in host defense. More recent research, however, has revealed that they also play a central role in mediating the skeletal muscle regenerative process.
Yan, Derek
core   +1 more source

Detection of the Strains Induced in Murine Tibias by Ex Vivo Uniaxial Loading with Different Sensors

Sensors, 2019
In this paper, the characterization of the main techniques and transducers employed to measure local and global strains induced by uniaxial loading of murine tibiae is presented.
Emanuele Rizzuto, Barbara Peruzzi, Mariagrazia Giudice, Enrica Urciuoli, Erika Pittella, Emanuele Piuzzi, Antonio Musarò, Zaccaria Del Prete   +7 more
doaj   +1 more source

Genetic and Clinical Predictors of Age of ESKD in Individuals With Autosomal Dominant Tubulointerstitial Kidney Disease Due to UMOD Mutations

Kidney International Reports, 2020
Introduction: Autosomal dominant tubulo-interstitial kidney disease due to UMOD mutations (ADTKD-UMOD) is a rare condition associated with high variability in the age of end-stage kidney disease (ESKD).
Kendrah Kidd, Petr Vylet’al, Céline Schaeffer, Eric Olinger, Martina Živná, Kateřina Hodaňová, Victoria Robins, Emily Johnson, Abbigail Taylor, Lauren Martin, Claudia Izzi, Sofia C. Jorge, Joaquim Calado, Rosa J. Torres, Karl Lhotta, Dominik Steubl, Daniel P. Gale, Christine Gast, Eva Gombos, Hannah C. Ainsworth, Ying Maggie Chen, Jorge Reis Almeida, Cintia Fernandes de Souza, Catarina Silveira, Rita Raposeiro, Nelson Weller, Peter J. Conlon, Susan L. Murray, Katherine A. Benson, Gianpiero L. Cavalleri, Miroslav Votruba, Alena Vrbacká, Antonio Amoroso, Daniela Gianchino, Gianluca Caridi, Gian Marco Ghiggeri, Jasmin Divers, Francesco Scolari, Olivier Devuyst, Luca Rampoldi, Stanislav Kmoch, Anthony J. Bleyer   +41 more
doaj   +1 more source

Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila [PDF]

, 2012
The respiratory (tracheal) system of the Drosophila melanogaster larva is an intricate branched network of air-filled tubes. Its developmental logic is similar in some ways to that of the vertebrate vascular system.
Jeon, Mili, Scott, Matthew P., Zinn, Kai
core   +3 more sources

The skeletal phenotype of chondroadherin deficient mice [PDF]

, 2013
Chondroadherin, a leucine rich repeat extracellular matrix protein with functions in cell to matrix interactions, binds cells via their a2b1 integrin as well as via cell surface proteoglycans, providing for different sets of signals to the cell ...
A Franzen, A Vortkamp, B Ganss, B Lanske, B Mansson, C Landgren, C Wiberg, Christiane Petzold, Christina Wenglén, Dick Heinegård, E Hedbom, Elizabeth K. Tanner, ES Baekkevold, Espen S. Baekkevold, Finn P. Reinholt, FP Reinholt, GK Hunter, Gunhild A. Stordalen, H Kojima, HY Zhou, J Sodek, JA Gordon, JM Johnson, K Hultenby, K Hultenby, KG Danielson, L Camper, L Svensson, Lovisa Hessle, M Mizuno, Nikos K. Karamanos, P Bianco, Patrik Önnerfjord, PJ Neame, R Fassler, S Chakravarti, SH Brorson, Sverre-Henning Brorson, T Hildebrand, T Larsson, T Xu, WJ Whitehouse, Y Sommarin, Y Sommarin, Z Shen   +44 more
core   +4 more sources

Perspective: Is Random Monoallelic Expression a Contributor to Phenotypic Variability of Autosomal Dominant Disorders?

Frontiers in Genetics, 2017
Several factors have been proposed as contributors to interfamilial and intrafamilial phenotypic variability in autosomal dominant disorders, including allelic variation, modifier genes, environmental factors and complex genetic and environmental ...
Baoheng Gui, Baoheng Gui, Jesse Slone, Taosheng Huang   +3 more
doaj   +1 more source

Arrhythmogenic Ventricular Cardiomyopathy

JACC: Case Reports, 2021
After a 20-year-old woman suddenly died, autopsy showed characteristic findings of biventricular arrhythmogenic cardiomyopathy. Screening of her family members revealed the same desmoplakin gene mutation and imaging abnormalities predominantly involving ...
Aranyak S. Rawal, MD, Tara VanCleave, BS, Neeraja Yedlapati, MD, Jeffery E. Saffitz, MD, PhD, William James Craigen, MD, PhD, John L. Jefferies, MD, MPH   +5 more
doaj   +1 more source

Effect of Media and Estrogen on Morphological Change in Candida albicans [PDF]

, 2020
Introduction: Candida albicans (C. albicans), an opportunistic pathogen, lives symbiotically within the intestine of its human host. Temperature and chemical factors have been shown to induce a morphological change in C.
Bouyer, Patrice G., Camp, Paige M., Watters, Michael K., Zachara, Idalia Z.   +3 more
core   +1 more source

Human infectivity trait in Trypanosoma brucei: stability, heritability and relationship to sra expression [PDF]

, 2004
Some Trypanosoma brucei lines infect humans whereas others do not because the parasites are lysed by human serum. We have developed a robust, quantitative in vitro assay based on differential uptake of fluorescent dyes by live and dead trypanosomes to ...
Bisoni, L., Lindergard, L.A.G., MacLeod, A., McLellan, S., Tait, A., Turner, C.M.R.   +5 more
core   +1 more source