Results 61 to 70 of about 3,800,975 (380)

Detection of the Strains Induced in Murine Tibias by Ex Vivo Uniaxial Loading with Different Sensors

Sensors, 2019
In this paper, the characterization of the main techniques and transducers employed to measure local and global strains induced by uniaxial loading of murine tibiae is presented.
Emanuele Rizzuto, Barbara Peruzzi, Mariagrazia Giudice, Enrica Urciuoli, Erika Pittella, Emanuele Piuzzi, Antonio Musarò, Zaccaria Del Prete   +7 more
doaj   +1 more source

Genetic and Clinical Predictors of Age of ESKD in Individuals With Autosomal Dominant Tubulointerstitial Kidney Disease Due to UMOD Mutations

Kidney International Reports, 2020
Introduction: Autosomal dominant tubulo-interstitial kidney disease due to UMOD mutations (ADTKD-UMOD) is a rare condition associated with high variability in the age of end-stage kidney disease (ESKD).
Kendrah Kidd, Petr Vylet’al, Céline Schaeffer, Eric Olinger, Martina Živná, Kateřina Hodaňová, Victoria Robins, Emily Johnson, Abbigail Taylor, Lauren Martin, Claudia Izzi, Sofia C. Jorge, Joaquim Calado, Rosa J. Torres, Karl Lhotta, Dominik Steubl, Daniel P. Gale, Christine Gast, Eva Gombos, Hannah C. Ainsworth, Ying Maggie Chen, Jorge Reis Almeida, Cintia Fernandes de Souza, Catarina Silveira, Rita Raposeiro, Nelson Weller, Peter J. Conlon, Susan L. Murray, Katherine A. Benson, Gianpiero L. Cavalleri, Miroslav Votruba, Alena Vrbacká, Antonio Amoroso, Daniela Gianchino, Gianluca Caridi, Gian Marco Ghiggeri, Jasmin Divers, Francesco Scolari, Olivier Devuyst, Luca Rampoldi, Stanislav Kmoch, Anthony J. Bleyer   +41 more
doaj   +1 more source

PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. [PDF]

, 2013
The database of genotypes and phenotypes (dbGaP) developed by the National Center for Biotechnology Information (NCBI) is a resource that contains information on various genome-wide association studies (GWAS) and is currently available via NCBI's dbGaP ...
Alipanah, Neda, Conway, Mike, Doan, Son, Farzaneh, Seena, Feupe, Stephanie Feudjio, Garland, Asher, Hsieh, Alex, Jiang, Xiaoqian, Kim, Hyeon-Eui, Lin, Ko-Wei, Ohno-Machado, Lucila, Ross, Mindy K, Walker, Rebecca, Xu, Hua, Zhang, Jing   +14 more
core   +3 more sources

Notes on the Genetics of \u3ci\u3ePhymatodes Testaceus\u3c/i\u3e (Coleoptera: Cerambycidae) [PDF]

, 2017
Phenotype ratio for elytral coloration among reared offspring of Phymatodes testaceus suggests that this trait is controlled by a single gene with a dominant allele producing brown elytra and a reeessive allele for blue elytra. The brown-elytra phenotype
Gosling, D. C. L
core   +2 more sources

Cancer Metabolism: Phenotype, Signaling and Therapeutic Targets

Cells, 2020
Aberrant metabolism is a major hallmark of cancer. Abnormal cancer metabolism, such as aerobic glycolysis and increased anabolic pathways, has important roles in tumorigenesis, metastasis, drug resistance, and cancer stem cells.
J. Park, Woo Yang Pyun, H. Park
semanticscholar   +1 more source

Perspective: Is Random Monoallelic Expression a Contributor to Phenotypic Variability of Autosomal Dominant Disorders?

Frontiers in Genetics, 2017
Several factors have been proposed as contributors to interfamilial and intrafamilial phenotypic variability in autosomal dominant disorders, including allelic variation, modifier genes, environmental factors and complex genetic and environmental ...
Baoheng Gui, Baoheng Gui, Jesse Slone, Taosheng Huang   +3 more
doaj   +1 more source

Arrhythmogenic Ventricular Cardiomyopathy

JACC: Case Reports, 2021
After a 20-year-old woman suddenly died, autopsy showed characteristic findings of biventricular arrhythmogenic cardiomyopathy. Screening of her family members revealed the same desmoplakin gene mutation and imaging abnormalities predominantly involving ...
Aranyak S. Rawal, MD, Tara VanCleave, BS, Neeraja Yedlapati, MD, Jeffery E. Saffitz, MD, PhD, William James Craigen, MD, PhD, John L. Jefferies, MD, MPH   +5 more
doaj   +1 more source

CXCL16/CXCR6 axis drives microglia/macrophages phenotype in physiological conditions and plays a crucial role in glioma [PDF]

, 2018
Microglia are patrolling cells that sense changes in the brain microenvironment and respond acquiring distinct phenotypes that can be either beneficial or detrimental for brain homeostasis.
Antonangeli, Fabrizio, D'Alessandro, Giuseppina, Esposito, Vincenzo, Lepore, Francesca, Limatola, Cristina, Santoro, Antonio, Trettel, Flavia   +6 more
core   +1 more source

OMIM.org: leveraging knowledge across phenotype–gene relationships

Nucleic Acids Res., 2018
For over 50 years Mendelian Inheritance in Man has chronicled the collective knowledge of the field of medical genetics. It initially cataloged the known X-linked, autosomal recessive and autosomal dominant inherited disorders, but grew to be the primary
J. Amberger, Carol A. Bocchini, A. F. Scott, A. Hamosh   +3 more
semanticscholar   +1 more source

Phenotype and Function of Activated Natural Killer Cells From Patients With Prostate Cancer: Patient-Dependent Responses to Priming and IL-2 Activation

Frontiers in Immunology, 2019
Background: Although immunotherapy has emerged as the “next generation” of cancer treatments, it has not yet been shown to be successful in the treatment of patients with prostate cancer, for whom therapeutic options remain limited to radiotherapy and ...
Simon P. Hood, Gemma A. Foulds, Heather Imrie, Stephen Reeder, Stéphanie E. B. McArdle, Masood Khan, Alan Graham Pockley   +6 more
doaj   +1 more source