Results 151 to 160 of about 26,955,799 (314)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Growing access to phenotype data [PDF]

Nature Genetics, 2015
openaire   +2 more sources

Open tools for quantitative anonymization of tabular phenotype data: literature review. [PDF]

Brief Bioinform, 2022
Haber AC, Sax U, Prasser F, NFDI4Health Consortium.   +3 more
europepmc   +1 more source

Neuronal expression of Ca2+ oscillation initiator is linked to rapid neonatal growth in mice

microPublication Biology, 2020
Woojin Kang, Kenji Yamatoya, Kenji Miyado, Mami Miyado, Yoshitaka Miyamoto   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Multimodal Genotype and Phenotype Data Integration to Improve Partial Data-Based Longitudinal Prediction. [PDF]

J Comput Biol, 2022
Ganjdanesh A, Zhang J, Yan S, Chen W, Huang H.   +4 more
europepmc   +1 more source

Spontaneous neoplasia in the western clawed frog Xenopus tropicalis

microPublication Biology, 2020
Makoto Suzuki, Takeshi Igawa, Nanoka Suzuki, Hajime Ogino, Haruki Ochi   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Wheat Trait and Phenotype Ontology

, 2015
Wheat Trait and Phenotype Ontology is an ontology of wheat traits and environmental factors that affect these traits. They include resistance to disease, development nutrition, bread quality, etc.
Sourdille, Pierre, Nédellec, Claire, Marcel, Thierry   +2 more
core   +1 more source

Measures for interoperability of phenotypic data

, 2018
Background: Plant phenotypic data shrouds a wealth of information which, when accurately analysed and linked to other data types, brings to light the knowledge about the mechanisms of life. As phenotyping is a field of research comprising manifold, diverse and time ‑consuming experiments, the findings can be fostered by reusing and combin‑ ing existing
Ćwiek-Kupczyńska, Hanna, Altmann, Thomas, Arend, Daniel, Arnaud, Elizabeth, Chen, Dijun, Cornut, Guillaume, Fiorani, Fabio, Frohmberg, Wojciech, Junker, Astrid, Klukas, Christian, Lange, Matthias, Mazurek, Cezary, Nafissi, Anahita, Neveu, Pascal, van Oeveren, Jan, Pommier, Cyril, Poorter, Hendrik, Rocca-Serra, Philippe, Sansone, Susanna-Assunta, Scholz, Uwe, van Schriek, Marco, Seren, Ümit, Usadel, Björn, Weise, Stephan, Kersey, Paul, Krajewski, Paweł   +25 more
openaire   +1 more source