Results 201 to 210 of about 26,955,799 (314)

DEFGermplasm: a comprehensive digital platform for forest genomic and phenotype data integration. [PDF]

open access: yesFor Res (Fayettev)
Du M   +13 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Mitochondrial DNA disease discovery through evaluation of genotype and phenotype data: The Solve-RD experience. [PDF]

open access: yesAm J Hum Genet
Ratnaike T   +7 more
europepmc   +1 more source

Identification of population-level differentially expressed genes in one-phenotype data. [PDF]

open access: yesBioinformatics, 2020
Xie J   +10 more
europepmc   +1 more source

Calx, a sodium/calcium exchanger, may affect lifespan in Drosophila melanogaster

open access: yesmicroPublication Biology, 2020
Jung-Wan Mok   +2 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

A partial T-DNA insertion near KNAT1 results in lobed Arabidopsis thaliana leaves

open access: yesmicroPublication Biology, 2020
Karah Moulton   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Causal Mediation Analysis for Integrating Exposure, Genomic, and Phenotype Data. [PDF]

open access: yesAnnu Rev Stat Appl
Yang H   +7 more
europepmc   +1 more source

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