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Cellular Phenotype Plasticity in Cancer Dormancy and Metastasis [PDF]

open access: yesFrontiers in Oncology, 2018
Cancer dormancy is a period of cancer progression in which residual tumor cells exist, but clinically remain asymptomatic for a long time, as well as resistant to conventional chemo- and radiotherapies.
Xiao Yang   +4 more
doaj   +2 more sources

Epigenetic conservation infers that colorectal cancer progenitors retain the phenotypic plasticity of normal colon [PDF]

open access: yesScientific Reports
Plasticity, or the ability to rapidly and reversibly change phenotypes, may help explain how a single progenitor cell eventually generates a tumor with many different cell phenotypes.
Kelly Street   +3 more
doaj   +2 more sources

The Application of the Geometric Morphometric Technique in Evaluating Sexual Dimorphism in the Body Shape of Aphaniops Hormozensis from Mehran and Shur Rivers (Hormozgan Basin) [PDF]

open access: yesتاکسونومی و بیوسیستماتیک, 2020
During 2018-2019, to investigate the sexual dimorphism in the body shape and morphological variations of Aphaniops hormozensis inhabiting in Mehran and Shur rivers of the Hormozgan basin using the geometric morphometric method, 80 specimens were ...
Atta Mouludi-Saleh   +2 more
doaj   +1 more source

Role of vascular smooth muscle cell clonality in atherosclerosis

open access: yesFrontiers in Cardiovascular Medicine, 2023
Atherosclerotic cardiovascular disease remains the leading cause of death worldwide. While many cell types contribute to the growing atherosclerotic plaque, the vascular smooth muscle cell (SMC) is a major contributor due in part to its remarkable ...
Lingfeng Luo   +10 more
doaj   +1 more source

Estimating the Differences of Light Capture Between Rows Based on Functional-Structural Plant Model in Simultaneous Maize-Soybean Strip Intercropping

open access: yes智慧农业, 2022
Intercropping creates a heterogeneous canopy and triggers plastic responses in plant growth and structural development. In order to quantify the effect of planting pattern, strip width and row position on the structural development and light capture of ...
LI Shuangwei   +6 more
doaj   +1 more source

Targeting drug‐tolerant cells: A promising strategy for overcoming acquired drug resistance in cancer cells

open access: yesMedComm, 2023
Drug resistance remains the greatest challenge in improving outcomes for cancer patients who receive chemotherapy and targeted therapy. Surmounting evidence suggests that a subpopulation of cancer cells could escape intense selective drug treatment by ...
Xiaohai Song   +13 more
doaj   +1 more source

Morphological Variations of Kura Barbel (Barbus Lacerta Heckel, 1843) from the Tigris River Basin using the Geometric Morphometric Method [PDF]

open access: yesتاکسونومی و بیوسیستماتیک, 2020
The present study was conducted to investigate the morphological variations in different populations of Barbus lacerta from the Iranian part of the Tigris River drainage using the geometric morphometric method.
Reyhan Mirmohammadi   +2 more
doaj   +1 more source

Emerging roles of endoplasmic reticulum stress in the cellular plasticity of cancer cells

open access: yesFrontiers in Oncology, 2023
Cellular plasticity is a well-known dynamic feature of tumor cells that endows tumors with heterogeneity and therapeutic resistance and alters their invasion–metastasis progression, stemness, and drug sensitivity, thereby posing a major challenge to ...
Hao Wang, Kun Mi
doaj   +1 more source

Phenotypic Plasticity in Juvenile Frogs That Experienced Predation Pressure as Tadpoles Does Not Alter Their Locomotory Performance

open access: yesBiology, 2023
Anuran species can respond to environmental changes via phenotypic plasticity, which can also result in ecological impacts across the life history of such species.
Junkyu Park, Yuno Do
doaj   +1 more source

Chronic Heat Stress Part 2: Increased Stress and Fear Responses in F1 Pekin Ducks Raised from Parents That Experienced Heat Stress

open access: yesAnimals, 2023
The effects of HS on the welfare of poultry have been reported to have a transgenerational effect on phenotype plasticity. The goal of our experiment was to determine whether parental exposure to HS would impair the performance, HPA axis response, or ...
Esther Mary Oluwagbenga   +3 more
doaj   +1 more source

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