The Genetic Architecture for Phenotypic Plasticity of the Rice Grain Ionome
The ionome of the rice grain is crucial for the health of populations that consume rice as a staple food. However, the contribution of phenotypic plasticity to the variation of rice grain ionome and the genetic architecture of phenotypic plasticity are ...
Yongjun Tan +5 more
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Phenotypic robustness can increase phenotypic variability after non-genetic perturbations in gene regulatory circuits [PDF]
Non-genetic perturbations, such as environmental change or developmental noise, can induce novel phenotypes. If an induced phenotype confers a fitness advantage, selection may promote its genetic stabilization. Non-genetic perturbations can thus initiate
Ancel +73 more
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Mapping the Plasticity of Morphology, Molecular Properties and Function in Mouse Primary Microglia
Microglia exert diverse functions by responding in diverse ways to different stimuli, yet little is known about the plasticity of various phenotypes that microglia display.
Xue Jiang +10 more
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Phenotypic flexibility and the evolution of organismal design [PDF]
Evolutionary biologists often use phenotypic differences between species and between individuals to gain an understanding of organismal design. The focus of much recent attention has been on developmental plasticity – the environmentally induced ...
Drent, Jan,, Piersma, Theunis,
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The selective advantage of reaction norms for environmental tolerance [PDF]
A tolerance curve defines the dependence of a genotype's fitness on the state of an environmental gradient. It can be characterized by a mode (the genotype's optimal environment) and a width (the breadth of adaptation). It seems possible that one or both
Gabriel, Wilfried, Lynch, Michael
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Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells
The transcription factor SNAI1 mediates epithelial-mesenchymal transition, fibroblast activation and controls inter-tissue migration. High SNAI1 expression characterizes metastatic triple-negative breast carcinomas, and its knockout by CRISPR/Cas9 ...
Chrysoula Tsirigoti +4 more
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Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation [PDF]
Plasticity in epithelial tissues relates to processes of embryonic development, tissue fibrosis and cancer progression. Pharmacological modulation of epithelial transitions during disease progression may thus be clinically useful.
Bellomo, C +12 more
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Effect of competitive cues on reproductive morphology and behavioral plasticity in male fruitflies [PDF]
Phenotypic plasticity will be favored whenever there are significant fitness benefits of responding to environmental variation. The extent and nature of the plasticity that evolves depends on the rate of environmental fluctuations and the capacity to ...
Bretman, Amanda +3 more
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The evolutionary ecology of interactive synchronism: The illusion of the optimal phenotype [PDF]
In this article, we discuss some ecological-evolutionary strategies that allow synchronization of organisms, resources, and conditions. Survival and reproduction require synchronization of life cycles of organisms with favourable environmental ...
Diniz-Filho, Jose Alexandre F +2 more
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