Results 21 to 30 of about 294,085 (294)
Genetic Assimilation and Canalisation in the Baldwin Effect [PDF]
, 2005 The Baldwin Effect indicates that individually learned behaviours acquired during an organism’s lifetime can influence the evolutionary path taken by a population, without any direct Lamarckian transfer of traits from phenotype to genotype.
C.H. Waddington +11 more
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Optimal phenotypic plasticity in a stochastic environment minimizes the cost/benefit ratio [PDF]
, 2012 This paper addresses the question of optimal phenotypic plasticity as a response to environmental fluctuations while optimizing the cost/benefit ratio, where the cost is energetic expense of plasticity, and benefit is fitness.
Coquillard, Patrick +2 more
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The conceptual structure of evolutionary biology: A framework from phenotypic plasticity [PDF]
, 2018 In this review, I approach the role of phenotypic plasticity as a key aspect of the conceptual framework of evolutionary biology. The concept of phenotypic plasticity is related to other relevant concepts of contemporary research in ...
Martins, Rogerio P
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Phenotypic plasticity during metastatic colonization
Trends in Cell Biology, 2022 Most solid cancer-related deaths result from metastasis, a multistep process in which cancer cells exit the primary site, intravasate into the bloodstream, extravasate, and colonize distant organs. Colonization is facilitated by clonal selection and the high phenotypic plasticity of cancer cells that creates reversible switching of cellular states ...
Jehanno, Charly +4 more
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Understanding and leveraging phenotypic plasticity during metastasis formation
npj Systems Biology and Applications, 2023 Cancer metastasis is the process of detrimental systemic spread and the primary cause of cancer-related fatalities. Successful metastasis formation requires tumor cells to be proliferative and invasive; however, cells cannot be effective at both tasks ...
Saumil Shah +5 more
doaj +1 more source
Insects, 2022 Developmental plasticity refers to the property by which a genotype corresponds to distinct phenotypes depending on the environmental conditions experienced during development.
Ana Rita Amaro Mateus, Patrícia Beldade
doaj +1 more source
Juxtaglomerular Cell Phenotypic Plasticity [PDF]
High Blood Pressure & Cardiovascular Prevention, 2017 Renin is the first and rate-limiting step of the renin-angiotensin system. The exclusive source of renin in the circulation are the juxtaglomerular cells of the kidney, which line the afferent arterioles at the entrance of the glomeruli. Normally, renin production by these cells suffices to maintain homeostasis.
Martini, Alexandre, Danser, Jan
openaire +2 more sources
Nature Communications, 2023 Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell lines according to their epigenetic landscapes and core regulatory circuitries.
Cécile Thirant +31 more
doaj +1 more source
Pre-reproductive parental enriching experiences influence progeny’s developmental trajectories [PDF]
, 2018 While the positive effects of environmental enrichment (EE) applied after weaning, in adulthood, during aging, or even in the presence of brain damage have been widely described, the transgenerational effects of pre-reproductive EE have been less ...
Berretta, Erica +5 more
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What can developmental disorders tell us about the neurocomputational constraints that shape development? the case of Williams syndrome [PDF]
, 2003 The uneven cognitive phenotype in the adult outcome of Williams syndrome has led some researchers to make strong claims about the modularity of the brain and the purported genetically determined, innate specification of cognitive modules.
Karmiloff-Smith, Annette +1 more
core +3 more sources