Results 81 to 90 of about 294,085 (294)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Phenotypic Plasticity: From Microevolution to Macroevolution [PDF]
, 2014 This chapter starts with a short history of the concept of phenotypic plasticity (from the seventeenth century to present) in order to distinguish two distinct conceptions of plasticity: one more dynamic (or Aristotelian) according to which the notion has been described as a property inherent to life whose very organization depends upon it, and an ...
openaire +1 more source
Effects of Rate of Drying, Life History Phase, and Ecotype on the Ability of the Moss Bryum Argenteum to Survive Desiccation Events and the Influence on Conservation and Selection of Material for Restoration [PDF]
, 2019 Desiccation stress is frequently experienced by the moss Bryum argenteum and can influence survival, propagation and niche selection. We attempted to disentangle the interacting factors of life history phase (five categories) and rate of desiccation ...
Chiquoine, Lindsay P. +2 more
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Macrophages in wound healing: activation and plasticity. [PDF]
, 2019 Macrophages are critically involved in wound healing, from dampening inflammation to clearing cell debris and coordinating tissue repair. Within the wound, the complexity of macrophage function is increasingly recognized, with adverse outcomes when ...
Kim, Sang Yong, Nair, Meera G
core
Environmentally induced phenotypic variation in wild yellow-bellied marmots [PDF]
, 2016 We thank all the marmoteers who helped in data collection and 2 anonymous reviewers who helped us to clarify our message. AM-C was supported by a Fulbright Fellowship, and JGAM was supported by Fond Québécois de Recherche sur la Nature et les ...
Armitage, Kenneth B. +4 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Time to exploit phenotypic plasticity [PDF]
Journal of Experimental Botany, 2020 This article comments on:Diouf I, Derivot L, Koussevitzky S, Carretero Y, Bitton F, Moreau L, Causse M. 2020. Genetic basis of phenotypic plasticity and genotype×environment interaction in a multi-parental tomato population. Journal of Experimental Botany 71, 5365–5376.
openaire +6 more sources
Evolution of generalists by phenotypic plasticity [PDF]
iScience, 2019 AbstractAdapting organisms face a tension between specializing their phenotypes for certain ecological tasks or developing generalist strategies which permit persistence in multiple environmental conditions. Understanding when and how generalists or specialists evolve is therefore an important question in evolutionary dynamics.
Fraebel, David T. +3 more
openaire +3 more sources