Results 111 to 120 of about 111,624 (298)

Visualization of phenotypic plasticity.

open access: yes, 2018
A schematic to demonstrate the effect of phenotypic plasticity on an outcome measure. Each line with a unique color represents a different genotype. (A) Behavior when there is no phenotypic plasticity showing an outcome that depends on the genotype but ...
Natasha A. Karp (107980)
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Phenotypic plasticity and diversity in insects [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2010
Phenotypic plasticity in general and polyphenic development in particular are thought to play important roles in organismal diversification and evolutionary innovation. Focusing on the evolutionary developmental biology of insects, and specifically that of horned beetles, I explore the avenues by which phenotypic plasticity and polyphenic development ...
openaire   +2 more sources

Differential phenotypic plasticity of subalpine trees predicts trait integration under climate warming

open access: yes
Summary Understanding limiting factors of phenotypic plasticity is essential given its critical role in shaping biological adaptation and evolution in changing environments.
Hu, M   +5 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Changes in selection regime cause loss of phenotypic plasticity in planktonic freshwater copepods.

open access: yesPLoS ONE, 2014
Rapid phenotypic adaptation is critical for populations facing environmental changes and can be facilitated by phenotypic plasticity in the selected traits.
Sergej Vital'evič Sereda   +2 more
doaj   +1 more source

Adaptation to climate in widespread eucalypt species [PDF]

open access: yes, 2013
The long term success of revegetation efforts will depend upon the planted species’ resilience to climate change. Many widespread species grow across a range of climatic conditions and, thus, may possess adaptations that could be utilised to improve ...
Suzanne Prober   +2 more
core  

Regulatory mechanisms link phenotypic plasticity to evolvability [PDF]

open access: yes, 2016
Organisms have a remarkable capacity to respond to environmental change. They can either respond directly, by means of phenotypic plasticity, or they can slowly adapt through evolution. Yet, how phenotypic plasticity links to evolutionary adaptability is
Weissing, Franz J.   +2 more
core   +1 more source

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