LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The genetic relationship between commencement of luteal activity and calving interval, body condition score, production, and linear type traits in Holstein-Friesian dairy cattle [PDF]
The decline of fertility in the UK dairy herd and the unfavorable genetic correlation (r(a)) between fertility and milk yield has necessitated the broadening of breeding goals to include fertility.
Flint, APF +7 more
core
A catalogue of validated single nucleotide polymorphisms in bovine orthologs of mammalian imprinted genes and associations with beef production traits [PDF]
peer-reviewedGenetic (or ‘genomic’) imprinting, a feature of approximately 100 mammalian genes, results in monoallelic expression from one of the two parentally inherited chromosomes. To date, most studies have been directed on imprinted genes in murine
Magee, David A +23 more
core +1 more source
【Objective】Phenotypic evaluation was performed on diverse Curcuma germplasm resources, followed by association analysis to identify markers significantly associated with flowering traits, thereby providing theoretical guidance for the breeding of ...
Yuanjun YE +8 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Phenotypic changes in different spinach varieties grown and selected under organic conditions [PDF]
Organic and low-input agriculture needs flexible varieties that can buffer environmental stress and adapt to the needs of farmers. We implemented an experiment to investigate the evolutionary capacities of a sample of spinach (Spinacia oleracea L ...
Goldringer, I. +17 more
core +1 more source
Phenotypic traits for female Savannah sparrows [PDF]
Phenotypic traits for female Savannah ...
Erik Postma (378595) +5 more
core +3 more sources
This study investigated leaf phenotypic variation in oak species to better understand how different groups of oaks adapt to diverse environmental conditions.
Xuan Li +4 more
doaj +1 more source
Phenotypic characteristics of linear traits of udder and angularity in Holstein-Friesian cows and their correlation with milk yield traits [PDF]
Data set including 10860 primiparous Holstein-Friesian breed cows first calved in the period from 2011 to 2015, was used in determining phenotypic variability and correlation between the traits of milk yield and linearly estimated traits of udder and ...
Đedović Radica +7 more
doaj

