Results 81 to 90 of about 192,777 (261)

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Dissection of heterogeneous phenotypes for quantitative trait mapping

Genetic Epidemiology, 2005
We discuss analyses of Genetic Analysis Workshop 14 data from the Collaborative Study on the Genetics of Alcoholism (COGA) as well as from a simulated complex disease, Kofendrerd personality disorder (KPD), with both genetic and phenotypic heterogeneity. Both data sets included numerous related phenotypes in addition to disease definitions.
Bickeboeller, Heike, Bailey, Julia N., Papanicolaou, G. J., Rosenberger, Albert, Viel, K. R.   +4 more
openaire   +3 more sources

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Study on Utilizing Mask R-CNN for Phenotypic Estimation of Lettuce’s Growth Status and Optimal Harvest Timing

Agronomy
Lettuce is an annual plant of the family Asteraceae. It is most often grown as a leaf vegetable, but sometimes for its stem and seeds, and its growth status and quality are evaluated based on its morphological phenotypic traits.
Lixin Hou, Yuxia Zhu, Ning Wei, Zeye Liu, Jixuan You, Jing Zhou, Jian Zhang   +6 more
doaj   +1 more source

Biochemical heterozygosity and phenotypic variability of polygenic traits [PDF]

Heredity, 1987
Using the theory of additive genetic variability of a polygenic trait, it is shown that an individual's heterozygosity at the loci governing the trait cannot be determined accurately from observations on phenotypes alone. Furthermore, the negative association between heterozygosity and phenotypic variance, and a positive correlation of the frequency of
openaire   +2 more sources

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source

Phenotypic and molecular diversity-based prediction of heterosis in pearl millet (Pennisetum glaucum L. (R.) Br.)

Crop Journal, 2018
Genetic distances between hybrid parents based on phenotypic traits and molecular markers were investigated to assess their relationship with heterosis for grain and stover yield and other traits in pearl millet (Pennisetum glaucum [L.] R. Br.).
Shashi Kumar Gupta, Thirunavukkarasu Nepolean, Chinna Ghouse Shaikh, Kedarnath Rai, Charles Thomas Hash, Roma Rani Das, Abhishek Rathore   +6 more
doaj   +1 more source

Genotypic and phenotypic correlation and path coefficient analysis for yield and yield-related traits in advanced bread wheat (Triticum aestivum L.) lines

Cogent Food & Agriculture, 2020
Information on the mutual association of traits is important for effective selection in plant-breeding program. Forty-nine advanced bread wheat lines were evaluated in western Amhara region with triple lattice design at two locations in 2018 main rainy ...
Ashebr Baye, Baye Berihun, Muluken Bantayehu, Bitwoded Derebe   +3 more
doaj   +1 more source

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High BMI: A Secondary Analysis of the IDEA Trial

Arthritis Care &Research, Accepted Article.
Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck, J. Elyse Borgert, Hyeon Lee, Liubov Arbeeva, Yvonne M. Golightly, Richard F. Loeser, Leigh F. Callahan, Stephen P. Messier, Brian Pietrosimone, Amanda E. Nelson, James S. Marron   +10 more
wiley   +1 more source

Genetic analysis of reproductive traits of Tianmu multiparous sheep

浙江大学学报. 农业与生命科学版
Reproductive traits are one of the important economic traits in the sheep industry. The purpose of this study was to explore the non-genetic factors affecting the reproductive traits of Tianmu multiparous sheep and their genetic parameters. In this study,
LI Xue, HONG Wei, LIU Guifen, WEI Chen, HE Junmin, ZHANG Guoping, ZHANG Wenjing, LONG Li, YANG Cunming, TIAN Kechuan, HUANG Xixia   +10 more
doaj   +1 more source