Results 71 to 80 of about 225,833 (307)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Phenotypic evolution and hidden speciation in Candidula unifasciata ssp. (Helicellinae, Gastropoda) inferred by 16S variation and quantitative shell traits [PDF]

, 2006
In an effort to link quantitative morphometric information with molecular data on the population level, we have analysed 19 populations of the conchologically variable land snail Candidula unifasciata from across the species range for variation in ...
Pfenninger, Markus, Magnin, Frédéric
core   +1 more source

Root Traits and Phenotyping Strategies for Plant Improvement [PDF]

Plants, 2015
Roots are crucial for nutrient and water acquisition and can be targeted to enhance plant productivity under a broad range of growing conditions. A current challenge for plant breeding is the limited ability to phenotype and select for desirable root characteristics due to their underground location.
Ana Paez-Garcia, Christy M. Motes, Wolf-Rüdiger Scheible, Rujin Chen, Elison B. Blancaflor, Maria J. Monteros   +5 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Relationships between lamb carcass quality traits measured by X-ray computed tomography (CT) and current UK-hill sheep breeding goals. [PDF]

, 2008
Genetic parameters were estimated between current UK hill sheep breeding goals and lamb carcass composition and muscularity traits derived using X-ray computed tomography (CT).
McLean, KA, McLaren, A., Lambe, NR; id_orcid, Bishop, S. C., Simm, Geoff, Lambe, N. R., Bünger, L., McLean, K. A., Conington, JE; id_orcid, McLaren, A; id_orcid, Bishop, SC, Simm, G, Bunger, L, Conington, J.   +13 more
core  

Prediction of breeding values and selection responses with genetic heterogeneity of environmental variance [PDF]

, 2007
There is empirical evidence that genotypes differ not only in mean, but also in environmental variance of the traits they affect. Genetic heterogeneity of environmental variance may indicate genetic differences in environmental sensitivity.
Mulder, H. A., H. A. Mulder, W. G. Hill, Mulder, H.A., Hill, W. G., Bijma, P., Hill, W.G., P. Bijma   +7 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Evaluation of Phenotypic Diversity of Daguotianyangtao in Guangxi

Guangdong nongye kexue, 2022
【Objective】The study was conducted to reveal the diversity of phenotypic traits of carambola leaves and explore the excellent germplasm resources so as to improve the protection and utilization of germplasm resources of Daguotianyangtao.【Method】Taking ...
Hangning LIU, Qingmei CHEN, Weizhong LIANG, Hui REN, Jingfei TIAN, Jiaxin LI, Yuhan CHEN, Qiong ZHOU   +7 more
doaj   +1 more source

Study on the Phenotypic Diversity of 33 Ornamental Xanthoceras sorbifolium Cultivars

Plants, 2023
Xanthoceras sorbifolium, belonging to the family Sapindaceae, has a beautiful tree shape, elegant leaves, large and many brightly colored flowers, and a long flowering duration. This plant is widely applied in gardens.
Chengyu Zhou, Huaiyan Wu, Qianqian Sheng, Fuliang Cao, Zunling Zhu   +4 more
doaj   +1 more source