Results 121 to 130 of about 1,168,358 (338)

Hypermethylator Phenotype in Sporadic Colon Cancer: Study on a Population-Based Series of 582 Cases [PDF]

, 2008
Ludovic Barault, Céline Charon‐Barra, Valérie Jooste, Mathilde Funes de la Vega, Laurent Martin, Patrick Roignot, Patrick Rat, Anne‐Marie Bouvier, Pierre Laurent‐Puig, Jean Faivre, Caroline Chapusot, F Piard   +11 more
openalex   +1 more source

Genetic diversity and population structure of a core collection of Mediterranean durum wheat accessions using DArTseq markers

BMC Genomics
Background Durum wheat was domesticated in the Fertile Crescent and later spread to the Mediterranean, where human and natural selection led to the establishment of local landraces.
Marwa Laribi, Sarrah Ben M’Barek, Sandra M. Velasco-Cuervo, Sheau-Fang Hwang, Amor H. Yahyaoui, Stephen E. Strelkov   +5 more
doaj   +1 more source

Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients: A Multicenter and Clinicopathological Study

Research
Metabolic dysfunction-associated steatohepatitis (MASH) is the progressive form of metabolic dysfunction-associated steatotic liver disease (MASLD), and closely associated with a high risk of liver-related morbidity and mortality.
Mengqi Fan, Erfei Song, Yuying Zhang, Pengfei Zhang, Bing Huang, Kaixuan Yan, Wah Yang, Subrata Chakrabarti, Hema Mahajan, Sen Yan, Ying Xu, Shuang Hua, Wei Liu, Cunchuan Wang, Aimin Xu, Dewei Ye   +15 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Trajectories of persisting Covid- 19 symptoms up to 24 months after acute infection: findings from the Predi-Covid cohort study

BMC Infectious Diseases
Introduction Long COVID is a multisystemic, fluctuating condition inducing a high burden on affected people. Despite the existence of some guidelines, its management remains complicated.
Aurélie Fischer, Lu Zhang, Abir Elbéji, Paul Wilmes, Chantal J. Snoeck, Jérôme Larché, Pauline Oustric, Markus Ollert, Guy Fagherazzi   +8 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Phenotyping adults with non-cystic fibrosis bronchiectasis: A prospective observational cohort study [PDF]

, 2013
Ghazanfar Ali Anwar, Melissa J. McDonnell, S A Worthy, Stephen C Bourke, G. Afolabi, Jim Lordan, Paul A. Corris, Anthony De Soyza, Peter G. Middleton, Chris Ward, Robert Rutherford   +10 more
openalex   +1 more source

Groundnut (Arachis hypogaea L.) improvement in sub-Saharan Africa: a review

Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, 2019
Groundnut (Arachis hypogaea L.) is a multi-purpose legume crop widely cultivated in sub-Saharan Africa (SSA). However, yield levels of the crop has remained relatively low in SSA owing to a range of biotic, abiotic and socio-economic constraints.
Seltene Abady, Hussein Shimelis, Pasupuleti Janila, Jacob Mashilo   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Root Phenotyping for Drought Tolerance: A Review

Agronomy, 2018
Plant roots play a significant role in plant growth by exploiting soil resources via the uptake of water and nutrients. Root traits such as fine root diameter, specific root length, specific root area, root angle, and root length density are considered ...
A. Wasaya, Xiying Zhang, Qin Fang, Zongzheng Yan   +3 more
semanticscholar   +1 more source