Results 31 to 40 of about 253,606 (273)

Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study [PDF]

open access: yes, 2016
There is an increasing interest for monitoring circulating myeloid-derived suppressor cells (MDSCs) in cancer patients, but there are also divergences in their phenotypic definition.
Brandau, Sven   +10 more
core   +2 more sources

1st INCF Workshop on Genetic Animal Models for Brain Diseases [PDF]

open access: yes, 2011
The INCF Secretariat organized a workshop to focus on the “role of neuroinformatics in the processes of building, evaluating, and using genetic animal models for brain diseases” in Stockholm, December 13–14, 2009.
Holm Graessner, Olaf Riess
core   +2 more sources

室内植物表型平台及性状鉴定研究进展和展望 [PDF]

open access: yes, 2020
Plant phenomics is under rapid development in recent years, a research field that is progressing towards integration, scalability, multi-perceptivity and high-throughput analysis.
Guohui, Ding   +6 more
core   +1 more source

Analytical Methodology for a Metabolome Atlas of Goat’s Plasma, Milk and Feces Using 1H-NMR and UHPLC-HRMS

open access: yesMetabolites, 2021
Metabolomics has been increasingly used in animal and food sciences. Animal health is one of the most important factor that can also alter animal integrity and welfare.
Cécile Martias   +9 more
doaj   +1 more source

Why Phenotype Robustness Promotes Phenotype Evolvability [PDF]

open access: yesGenome Biology and Evolution, 2017
Robustness and evolvability are fundamental characteristics of life whose relationship has intrigued generations of biologists. Studies of several genotype-phenotype maps (GPMs) such as the map between short DNA sequences and their bindings to transcription factors showed that phenotype robustness (PR) promotes phenotype evolvability (PE), but the ...
Wei, Xinzhu, Zhang, Jianzhi
openaire   +2 more sources

Survival phenotype, selfish individual versus Darwinian phenotype [PDF]

open access: yesJournal of Theoretical Biology, 2017
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Garay, József   +2 more
openaire   +2 more sources

Targeted mutagenesis in mouse cells and embryos using an enhanced prime editor

open access: yesGenome Biology, 2021
Prime editors, novel genome-editing tools consisting of a CRISPR-Cas9 nickase and an engineered reverse transcriptase, can induce targeted mutagenesis. Nevertheless, much effort is required to optimize and improve the efficiency of prime-editing. Herein,
Soo-Ji Park   +11 more
doaj   +1 more source

Efficient Replication of Over 180 Genetic Associations with Self-Reported Medical Data [PDF]

open access: yes, 2011
While the cost and speed of generating genomic data have come down dramatically in recent years, the slow pace of collecting medical data for large cohorts continues to hamper genetic research. Here we evaluate a novel online framework for amassing large
Amy K. Kiefer   +10 more
core   +6 more sources

Phenotyping the Microcirculation [PDF]

open access: yesHypertension, 2012
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidney. Both functional and structural alterations in the small arteries, arterioles, and capillaries are the
Struijker-Boudier, Harry A.J.   +3 more
openaire   +3 more sources

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