New Artificial Biomimetic Enzyme Analogues based on Iron(II/III) Schiff Base Complexes: An Effect of (Benz)imidazole Organic Moieties on Phenoxazinone Synthase and DNA Recognition. [PDF]
Elucidation of the structure and function of biomolecules provides us knowledge that can be transferred into the generation of new materials and eventually applications in e.g., catalysis or bioassays.
Bocian A +8 more
europepmc +2 more sources
Bioactive Nitrosylated and Nitrated N-(2-hydroxyphenyl)acetamides and Derived Oligomers: An Alternative Pathway to 2-Amidophenol-Derived Phytotoxic Metabolites. [PDF]
Incubation of Aminobacter aminovorans, Paenibacillus polymyxa, and Arthrobacter MPI764 with the microbial 2-benzoxazolinone (BOA)-degradation-product 2-acetamido-phenol, produced from 2-aminophenol, led to the recently identified N-(2-hydroxy-5 ...
Girel S +4 more
europepmc +2 more sources
Synthesis, spectroscopic study, antioxidant, DNA-cleavage and enzyme-mimicking activities for metal<sup>(II/III)</sup> complexes with azo ligand-eugenol scaffold. [PDF]
A newly synthesized azo ligand, 1-((5-allyl-2-hydroxy-3-methoxyphenyl)diazenyl)anthracene-9,10-dione (H-MND), derived from an anthraquinone nucleus coupled with the natural phenol (eugenol), was employed to prepare Co(II), Ni(II), Cu(II), Rh(III) and Pd ...
Nafea HM, Salih Al-Hamdani AA.
europepmc +2 more sources
Complete Genome Sequencing of Polar Arthrobacter sp. PAMC25284, Copper Tolerance Potential Unraveled with Genomic Analysis. [PDF]
The genus Arthrobacter is a known group of Gram‐positive, opportunistic pathogenic bacteria from cold climates, with members that are believed to play a variety of roles at low temperatures. However, their survival mechanisms in frigid environments like the Antarctic are still unknown.
Karmacharya J +4 more
europepmc +2 more sources
Steric control of copper nuclearity in sulfur ligated oxidase mimics alters catechol and phenoxazinone oxidation. [PDF]
Control over copper nuclearity is a key issue in bioinspired oxidation chemistry, yet its mechanistic consequences in sulfur-donor environments remain insufficiently understood.
Khalaf EI +5 more
europepmc +2 more sources
3-Hydroxykynurenine in Regulation of Drosophila Behavior: The Novel Mechanisms for Cardinal Phenotype Manifestations. [PDF]
Dysfunctions of kynurenine pathway of tryptophan metabolism (KPTM) are associated with multiple neuropathologies in vertebrates and invertebrates.
Zhuravlev AV +3 more
europepmc +2 more sources
New Streptomyces-Derived Antibacterial Compounds Targeting Gram-Positive Bacteria: A Systematic Review. [PDF]
Bacterial infections, particularly those caused by Gram‐positive bacteria like vancomycin‐resistant enterococci (VRE) and methicillin‐resistant Staphylococcus aureus (MRSA), are a growing concern. This review highlights the potential of the Streptomyces genus in producing novel antibacterial compounds against Gram‐positive bacteria.
Ait Assou S, El Hassouni M.
europepmc +2 more sources
Enzymatic and non-enzymatic pathways of kynurenines' dimerization: the molecular factors for oxidative stress development. [PDF]
Kynurenines, the products of tryptophan oxidative degradation, are involved in multiple neuropathologies, such as Huntington's chorea, Parkinson's disease, senile dementia, etc.
Zhuravlev AV +2 more
europepmc +2 more sources
Towards Efficient Catalysts via Biomimetic Chemistry for Diphenols and Aminophenols Aerobic Oxidation [PDF]
Biomimetic chemistry is a new environment-friendly approach that is inspired by biological processes, to produce new catalysts, and to develop ‘green’ synthetic routes to chemical catalysts based on the benefits of biological systems, aimed to find ...
Abdeslam Mouadili +2 more
doaj +1 more source
There are increasing efforts towards the development of new synthetic models that can mimic phenoxazinone synthase activity due to the important applications of several biomolecules bearing the phenoxazinone chromophore.
Oloyede, Hammed Olawale +4 more
doaj +1 more source

