Results 61 to 70 of about 55,307 (220)

Variation in Microbiome Composition and Faecal Metabolites Are Associated With Differential Susceptibility to DSS‐Induced Colitis

Immunology, EarlyView.
C57BL/6 mice from Charles River Laboratories (CR) have enhanced mucosal immune action relative to C57BL/6 mice from Jackson Laboratories (JAX). CR mice are more susceptible to severe DSS‐induced colitis than JAX mice. Co‐housing transfers colitis susceptibility from CR mice to JAX mice.
Jessica M. Till, Orion D. Brock, Elyza A. Do, Morgan J. Engelhart, Robert W. P. Glowacki, Shaomin Hu, Ansel Hsiao, Ina Nemet, Philip P. Ahern   +8 more
wiley   +1 more source

2-Methoxy-2-phenylacetic acid

Acta Crystallographica Section E Structure Reports Online, 2003
2-Methoxy-2-phenyl­acetic acid, C9H10O3, forms helical columns of single enantiomers linked by hydrogen bonding between the acidic proton of one mol­ecule and the methoxy O atom of a neighbouring mol­ecule, to give an overall racemic structure.
Jens Hartung, Kristina Špehar, Ingrid Svoboda, Hartmut Fuess   +3 more
openaire   +1 more source

B(OCH2CF3)3-mediated direct amidation of pharmaceutically relevant building blocks in cyclopentyl methyl ether [PDF]

, 2015
The use of B(OCH2CF3)3 for mediating direct amidation reactions of a wide range of pharmaceutically relevant carboxylic acids and amines is described, including numerous heterocycle-containing examples.
Badland, M, Karaluka, V, Lanigan, RM, Murray, PM, Sheppard, TD   +4 more
core   +1 more source

Host‐Induced Silencing of Rhizoctonia Solani 5‐Enolpyruvylshikimate‐3‐Phosphate Synthase Impairs Its Virulence in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar, Apoorva Prasad, Akshita Goel, Vijay Kumar Sharma, Jagjeet Singh Lore, Arun Kumar   +5 more
wiley   +1 more source

Production of a recombinant membrane protein in an Escherichia coli strain for the whole cell biosynthesis of phenylacetic acids

Biotechnology Reports, 2015
The styrene oxide isomerase (SOI) represents a membrane-bound enzyme of the microbial styrene degradation pathway and has been discussed as promising biocatalyst. It catalyzes the isomerization of styrene oxide to phenylacetaldehyde. In this study a styC
Michel Oelschlägel, Claudia Heiland, Michael Schlömann, Dirk Tischler   +3 more
doaj   +1 more source

Fractionation of the mixture obtained by the enzymatic hydrolysis of penicillin G [PDF]

Hemijska Industrija, 2002
Using the experimental data on the individual physical and reactive extraction of 6APA with 1,2-dichlororethane, D2EHPA and Amberlite LA-2 together with data on the influence of the pH value of the aqueous phase and the Amberlite LA-2 concentration on ...
Cascaval Dan, Oniscu Corneliu, Galaction Anca-Irina   +2 more
doaj   +1 more source

Catabolism of phenylacetic acid in Penicillium rubens. Proteome-wide analysis in response to the benzylpenicillin side chain precursor [PDF]

, 2018
Biosynthesis of benzylpenicillin in filamentous fungi (e.g. Penicillium chrysogenum - renamed as Penicillium rubens- and Aspergillus nidulans) depends on the addition of CoA-activated forms of phenylacetic acid to isopenicillin N.
Barreiro, Carlos., Domínguez-Santos, Rebeca., García-Estrada, Carlos., Jami, Mohammad-Saeid., Martín, Juan-Francisco., Pascual, María., Vasco-Cárdenas, María-Fernanda.   +6 more
core  

Protein–phenolic interactions and inhibition of glycation – combining a systematic review and experimental models for enhanced physiological relevance [PDF]

, 2014
Background: While antiglycative capacity has been attributed to (poly)phenols, the exact mechanism of action remains unclear. Studies so far are often relying on supra-physiological concentrations and use of non-bioavailable compounds.<p></p>
Combet, E., Lean, M.E.J., Vlassopoulos, A.   +2 more
core   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Chemogenetic activation of mammalian brain neurons expressing insect Ionotropic Receptors by systemic ligand precursor administration

Communications Biology
Chemogenetic approaches employing ligand-gated ion channels are advantageous regarding manipulation of target neuronal population functions independently of endogenous second messenger pathways.
Yoshio Iguchi, Ryoji Fukabori, Shigeki Kato, Kazumi Takahashi, Satoshi Eifuku, Yuko Maejima, Kenju Shimomura, Hiroshi Mizuma, Aya Mawatari, Hisashi Doi, Yilong Cui, Hirotaka Onoe, Keigo Hikishima, Makoto Osanai, Takuma Nishijo, Toshihiko Momiyama, Richard Benton, Kazuto Kobayashi   +17 more
doaj   +1 more source