Results 91 to 100 of about 390,444 (399)

Phenylalanine Increases Membrane Permeability.

Journal of the American Chemical Society, 2017
Biological membranes are a crucial aspect of living systems, controlling the organization and distribution of different chemical components. Control of membrane permeability is especially important for processes such as electron transport in metabolism ...
Russell J. Perkins, V. Vaida
semanticscholar   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

A FLUORESCENCE, 1H NMR SPECTROSCOPY AND MOLECULAR DYNAMICS STUDY OF THE INFLUENCE OF ROTAMER POPULATION ON FLUORESCENCE DECAY OF TYROSINE, PHENYLALANINE AND THEIR DERIVATIVES

TASK Quarterly, 2001
Molecular dynamics simulations were carried out on tyrosine and phenylalanine and their derivatives with various terminal groups to determine the populations of side-chain rotamers.
ROBERT GANZYNKOWICZ, ADAM LIWO, WIESŁAW WICZK   +2 more
doaj  

An important role of the pepper phenylalanine ammonia-lyase gene (PAL1) in salicylic acid-dependent signalling of the defence response to microbial pathogens

Journal of Experimental Botany, 2014
Summary Phenylalanine ammonia-lyase (PAL) is an inducible enzyme that responds to biotic and abiotic stresses. Results suggest the potential significance of pepper PAL1 in the plant defence response to microbial pathogens.
Dae Sung Kim, B. Hwang
semanticscholar   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Rapid one-step separation and purification of recombinant phenylalanine dehydrogenase in aqueous two-phase systems [PDF]

, 2008
Background: Phenylalanine dehydrogenase (PheDH; EC 1.4.1.20) is a NAD +-dependent enzyme that performs the reversible oxidative deamination of L-phenylalanine to phenylpyruvate.
Mohammadi, H.S., Omidinia, E., Taherkhani, H.   +2 more
core  

Detachment of semiflexible polymer chains from a substrate - a Molecular Dynamics investigation

, 2014
Using Molecular Dynamics simulations, we study the force-induced detachment of a coarse-grained model polymer chain from an adhesive substrate. One of the chain ends is thereby pulled at constant speed off the attractive substrate and the resulting saw ...
Erbas, A., Milchev, A., Paturej, J., Rostiashvili, V. G.   +3 more
core   +1 more source

The cardiovascular phenotype of adult patients with phenylketonuria [PDF]

, 2019
BACKGROUND: Patients with Phenylketonuria (PKU) are exposed to multiple cardiovascular risk factors, but the clinical significance of these abnormalities is yet unknown.
Azabdaftari, Aline, Giet, Markus van der, Hennermann, Julia B., Plöckinger, Ursula, Querfeld, Uwe, Schuchardt, Mirjam   +5 more
core   +1 more source

Improving the Production of L-Phenylalanine by Identifying Key Enzymes Through Multi-Enzyme Reaction System in Vitro

Scientific Reports, 2016
L-Phenylalanine (L-Phe) is an important amino acid used in both food and medicinal applications. We developed an in vitro system that allowed a direct, quantitative investigation of phenylalanine biosynthesis in E. coli. Here, the absolute concentrations
D. Ding, Yongfei Liu, Yiran Xu, Ping Zheng, Haixing Li, Dawei Zhang, Jibin Sun   +6 more
semanticscholar   +1 more source

Effect of glucagon on phenylalanine metabolism and phenylalanine-degrading enzymes in the rat [PDF]

Biochemical Journal, 1974
Glucagon administered subcutaneously to rats for 10 days had no significant effect on liver phenylalanine hydroxylase activity, but induced liver dihydropteridine reductase more than twofold. In rats administered a phenylalanine load orally, glucagon treatment stimulated oxidation and depressed urinary phenylalanine excretion. These responses could not
Larry M. Brand, Alfred E. Harper
openaire   +3 more sources