Results 181 to 190 of about 207,395 (242)

Dual‐Mode Thio‐MacMillan Organocatalysts: Stereoselective Diels–Alder Reactions or Sacrificial Self‐Cyclization to N‐Bridged Bicyclic Lactams

open access: yesChemistry – A European Journal, EarlyView.
The study of the Diels–Alder reaction of cinnamaldehyde and cyclopentadiene, catalyzed by chiral imidazolidine‐4‐thiones, led to the discovery of a highly regio‐ and stereoselective Michael‐addition and consecutive ring closure. Here, the imidazolidine‐4‐thione not only catalytically activates cinnamaldehyde but also participates as the nucleophile to ...
Marian S. R. Ebeling   +5 more
wiley   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

open access: yesChemistry – A European Journal, EarlyView.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito   +3 more
wiley   +1 more source

A Tandem Chemical Vapor Deposition Platform for the Solvent‐Free Synthesis of Polypeptide Architectures

open access: yesChemistry – A European Journal, EarlyView.
A solvent‐free, two‐step chemical vapor polymerization enables efficient, substrate‐independent synthesis of surface‐attached polypeptide films. Initiator deposition via CVD is followed by NCA ring‐opening polymerization. Characterization confirms film formation and functionalization, allowing precise micropatterning and bioactive surface design for ...
Domenic Kratzer   +4 more
wiley   +1 more source

Phenylalanine amide derivatives promote FLG expression via AHR activation in normal human epidermal keratinocytes

open access: gold
Akiko Sumitomo   +7 more
openalex   +1 more source

Effect of soiling agents on disinfection efficacy of a pulsed‐xenon UV lamp towards Listeria monocytogenes on stainless steel surfaces

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
This study quantifies the effects of different soils found in the food processing environment on the efficiency of pulsed‐xenon UV disinfection. Abstract Listeria monocytogenes is a foodborne illness that poses a significant threat to human health in young, old, and immunocompromised persons and accordingly, prevention of Listeria contamination is of ...
Nazanin Yasoubi   +2 more
wiley   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka   +12 more
wiley   +1 more source

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