Results 181 to 190 of about 425,330 (380)

Flexible Crystals, Polymorph Selection and Interface Engineering for Organic Electronics: How New Discoveries and Established Knowledge Can Provide New Stimuli for Research Into Organic Semiconducting Single Crystals

open access: yesAdvanced Electronic Materials, EarlyView.
This work reviews recent advances in Organic Semiconducting Single Crystals (OSSCs), focusing on mechanical flexibility for robust devices, polymorph control for precise phase selection, and interface engineering with self‐assembled monolayers to improve alignment and performance.
Alessando Fraleoni‐Morgera   +3 more
wiley   +1 more source

Non-proteinaceous hydrolase comprised of a phenylalanine metallo-supramolecular amyloid-like structure

open access: yesNature Catalysis, 2019
Pandeeswar Makam   +7 more
semanticscholar   +1 more source

Fimbriae‐Targeted Peptide‐Selenoviologen Cyclophane Complex for Enhanced Photodynamic Therapy of Periodontitis

open access: yesAggregate, EarlyView.
This study develops a supramolecular photosensitizer (SeVB⊃PQ) by combining SeVB with a P. gingivalis‐targeting peptide. SeVB⊃PQ selectively binds P. gingivalis, boosts ROS generation under irradiation, disrupts ATP synthesis, restores microbial balance, reduces inflammation, and promotes alveolar bone regeneration, offering a promising platform for ...
Rui Ding   +7 more
wiley   +1 more source

Overcoming Clinical Barriers: Utilizing Self‐Assembly Systems to Break the Protease Limitations of Antimicrobial Peptides

open access: yesAggregate, EarlyView.
This study addresses AMPs' clinical application challenges by enhancing stability via molecular assembly. Pba* shows high antibacterial activity, biocompatibility, and low toxicity, paving the way for antimicrobial materials. ABSTRACT Natural antimicrobial peptides (AMPs) encounter significant challenges in transitioning to clinical application ...
Xu Guo   +7 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

open access: yesAngewandte Chemie, EarlyView.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet   +7 more
wiley   +2 more sources

Full‐Length FUS Protein Condensates Adopt a Domain‐Preferential Spatial Architecture

open access: yesAggregate, EarlyView.
We demonstrate a domain‐specific preferential distribution organization of FUS condensate and propose a sequence–structure–function paradigm for biomolecular condensates. ABSTRACT Biomolecular condensates play crucial roles in cellular physiology and are implicated in neurodegenerative diseases and cancer.
Si‐Cheng Tong   +5 more
wiley   +1 more source

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

open access: yesAngewandte Chemie, EarlyView.
This review presents the latest advances in the development of ruthenium complexes within the field of protein science, highlighting their potential applications in biomedical and bioanalytical fields. Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years,
Liyan Zhang, Yun Chen, Sylvestre Bonnet
wiley   +2 more sources

Development of an Interaction Model of the Protein–Nanocluster Interface by Machine Learning–Assisted Clustering of Amino Acids

open access: yesAggregate, EarlyView.
An interaction model for the interface between ligand‐protected gold nanoclusters and proteins is developed using unsupervised machine learning techniques and validated by molecular dynamics simulations and density functional theory calculations. ABSTRACT The interactions that occur in the interface of proteins and ligand‐stabilised metal nanoclusters ...
Brenda Ferrari   +3 more
wiley   +1 more source

Thiosulfonate‐Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling

open access: yesAngewandte Chemie, EarlyView.
We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Lucie Šálková   +4 more
wiley   +2 more sources

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