Results 111 to 120 of about 178,348 (314)

An isotope dilution model for partitioning of phenylalanine and tyrosine uptake by the liver of lactating dairy cows [PDF]

open access: yes, 2018
An isotope dilution model to describe the partitioning of phenylalanine (PHE) and tyrosine (TYR) in the bovine liver was developed. The model comprises four intracellular and six extracellular pools and various flows connecting these pools and external ...
A. Bannink   +29 more
core   +1 more source

GmMYB4 Positively Regulates Isoflavone Biosynthesis via the GmMAPK6‐GmMYB4‐MBW Module in Soybean

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Isoflavones, a class of bioactive compounds predominantly found in leguminous plants, are largely responsible for their beneficial effects on human health. Although MYB transcription factors (TFs) are known to be crucial regulators of isoflavone biosynthesis in soybean, the precise mechanisms underlying their regulatory functions remain poorly
Changyun Yang   +12 more
wiley   +1 more source

The Reaction Mechanism of Phenylalanine Hydroxylase. – A Question of Coordination

open access: yesPteridines, 2005
Phenylalanine hydroxylase (PAH) is a non-heme iron and tetrahydrobiopterin-dependent enzyme that catalyzes the hydroxylation of L-phenylalanine to L-tyrosine using dioxygen as additional substrate.
Teigen Knut   +2 more
doaj   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador   +5 more
wiley   +1 more source

Trastornos neurológicos a consecuencia de la mutación del gen que codifica para fenilalanina hidroxilas

open access: yesRevista Ciencias Biomédicas, 2013
Introduction: Phenylketonuria (PKU) is an error of the metabolism of the amino acids due to the gene mutation that codifies for the enzyme called phenylalanine hydroxylase (PAH). 564 cases of mutations in different exons have been reported.
Alvear-Sedán Ciro   +2 more
doaj  

Histopathological Effects on the Eye Development During Perinatal Growth of Albino Rats Maternally Treated with Experimental Phenylketonuria During Pregnancy [PDF]

open access: yes, 2016
Phenylketonuria (PKU) is a genetic disorder that is characterized by an inability of the body to utilize the essential amino acid, phenylalanine. The disease results from a deficiency in phenylalanine hydroxylase, the enzyme catalyzing the conversion of ...
Ebied, H. M. (Hala)   +3 more
core  

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang   +6 more
wiley   +1 more source

Phenylketonuria and glycogen storage disease type III in sibs of one family

open access: yesThe Turkish Journal of Pediatrics, 2002
Hyperphenylalaninemia result from a block in the conversion of phenylalanine into tyrosine due to a defect in either the enzyme phenylalanine hydroxylase (98% of subjects) or in the metabolism of the cofactor tetrahydrobiopterin.
Tuncay Yilmazer   +5 more
doaj  

Development of an Efficient Strategy to Improve Extracellular Polysaccharide Production of Ganoderma lucidum Using L-Phenylalanine as an Enhancer

open access: yesFrontiers in Microbiology, 2019
Ganoderma lucidum has been a well-known species of basidiomycetes for a long time, and has been widely applied in the fields of food and medicine. Based on the simulation results of model iZBM1060 in our previous research, the effect of L-phenylalanine ...
Zhongbao Ma   +15 more
doaj   +1 more source

Tetrahydrobiopterin Deficiency: From Phenotype to Genotype [PDF]

open access: yes, 2017
As a result of the selective screening worldwide during the last 18 years, approximately 250 patients with tetrahydrobiopterin deficiency were discovered.
Blau, Nenad   +3 more
core  

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