Plant, Cell &Environment, EarlyView.ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador +5 more
wiley +1 more source
The Reaction Mechanism of Phenylalanine Hydroxylase. – A Question of Coordination
Pteridines, 2005 Phenylalanine hydroxylase (PAH) is a non-heme iron and tetrahydrobiopterin-dependent enzyme that catalyzes the hydroxylation of L-phenylalanine to L-tyrosine using dioxygen as additional substrate.
Teigen Knut +2 more
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Plant, Cell &Environment, EarlyView.ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang +6 more
wiley +1 more source
Phenylketonuria and glycogen storage disease type III in sibs of one family
The Turkish Journal of Pediatrics, 2002 Hyperphenylalaninemia result from a block in the conversion of phenylalanine into tyrosine due to a defect in either the enzyme phenylalanine hydroxylase (98% of subjects) or in the metabolism of the cofactor tetrahydrobiopterin.
Tuncay Yilmazer +5 more
doaj
A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis
Plant, Cell &Environment, EarlyView.ABSTRACT Engineering plants with reduced lignin content can result in pleiotropic growth defects. In stems of Arabidopsis plants with reduced expression of hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT), the plastidial glucose 6‐phosphate: phosphate co‐transporter GPT2 is highly overexpressed, and this coincides with reduced lignin ...
Aditi Subramani Raju +4 more
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The spectrum of phenylalanine hydroxylase variants and genotype-phenotype correlation in phenylketonuria patients in Gansu, China. [PDF]
Hum Genomics, 2023 Zhang C +13 more
europepmc +1 more source
Dark side of anthocyanin pigmentation
Plant Biology, EarlyView.This review examines dark anthocyanin pigmentation in plants by outlining its distribution, exploring the genetic mechanisms behind its development, and discussing its ecological role together with its potential for various industrial applications. Abstract Dark pigmentation can be observed in various parts of the plant, ranging from foliage to petals ...
K. Wolff, B. Pucker
wiley +1 more source
Systematic literature review of the somatic comorbidities experienced by adults with phenylketonuria
Orphanet Journal of Rare DiseasesBackground Phenylketonuria (PKU) is an inborn error of phenylalanine (Phe) metabolism that, if untreated, causes Phe accumulation in the brain leading to neurophysiologic alterations and poor outcomes.
Kaleigh B. Whitehall +17 more
doaj +1 more source
Characterization of phenylalanine hydroxylase gene variants and analysis of genotype-phenotype correlation in patients with phenylalanine hydroxylase deficiency from Fujian Province, Southeastern China. [PDF]
Mol Biol Rep, 2022 Zhou J +6 more
europepmc +1 more source
72 Phenylalanine Hydroxylase Activity in Hyperphenylalanernia [PDF]
, 1967 Margaret E. O’Flynn +3 more
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