Results 11 to 20 of about 66,253 (217)

Phenylephrine [PDF]

Reactions Weekly, 2020
semanticscholar   +7 more sources

Effects of phenylephrine on systemic and cerebral circulations in humans: a systematic review with mechanistic explanations

Anaesthesia, 2023
We conducted a systematic review of the literature reporting phenylephrine‐induced changes in blood pressure, cardiac output, cerebral blood flow and cerebral tissue oxygen saturation as measured by near‐infrared spectroscopy in humans.
L. Meng, Y. Sun, X. Zhao, D. Meng, Z. Liu, D. C. Adams, D. L. McDonagh, M. Rasmussen   +7 more
semanticscholar   +1 more source

Cerebral Macro- and Microcirculation during Ephedrine versus Phenylephrine Treatment in Anesthetized Brain Tumor Patients: A Randomized Clinical Trial Using Magnetic Resonance Imaging

Anesthesiology, 2021
Background: This study compared ephedrine versus phenylephrine treatment on cerebral macro- and microcirculation, measured by cerebral blood flow, and capillary transit time heterogeneity, in anesthetized brain tumor patients.
K. U. Koch, I. Mikkelsen, U. Espelund, Hugo Angleys, A. Tietze, G. Oettingen, N. Juul, L. Østergaard, M. Rasmussen   +8 more
semanticscholar   +1 more source

Norepinephrine or phenylephrine during spinal anaesthesia for Caesarean delivery: a randomised double-blind pragmatic non-inferiority study of neonatal outcome.

British Journal of Anaesthesia, 2020
BACKGROUND Norepinephrine is an effective vasopressor during spinal anaesthesia for Caesarean delivery. However, before it can be fully recommended, possible adverse effects on neonatal outcome should be excluded.
W. N. Ngan Kee, Shara W. Y. Lee, F. Ng, Anna Lee   +3 more
semanticscholar   +1 more source

A systematic review of phenylephrine vs. noradrenaline for the management of hypotension associated with neuraxial anaesthesia in women undergoing caesarean section

Anaesthesia, 2020
Phenylephrine is recommended for the management of hypotension after spinal anaesthesia in women undergoing caesarean section. Noradrenaline, an adrenergic agonist with weak β‐adrenergic activity, has been reported to have a more favourable haemodynamic ...
M. Heesen, N. Hilber, K. Rijs, R. Rossaint, T. Girard, F. Mercier, Markus Klimek   +6 more
semanticscholar   +1 more source

Nitric oxide-mediated inhibition of phenylephrine-induced contraction in response to hypothermia is partially modulated by endothelial Rho-kinase

International Journal of Medical Sciences, 2020
This study examined the possible upstream cellular signaling pathway associated with nitric oxide (NO)-mediated inhibition of phenylephrine-induced contraction in isolated rat aortae in response to mild hypothermia, with a particular focus on endothelial
S. Lee, S. Ok, R. Subbarao, Ji-Yon Kim, S. Bae, Yeran Hwang, Seongyeong Tak, J. Sohn   +7 more
semanticscholar   +1 more source

Ephedrine versus Phenylephrine Effect on Cerebral Blood Flow and Oxygen Consumption in Anesthetized Brain Tumor Patients: A Randomized Clinical Trial.

Anesthesiology, 2020
BACKGROUND Studies in anesthetized patients suggest that phenylephrine reduces regional cerebral oxygen saturation compared with ephedrine. The present study aimed to quantify the effects of phenylephrine and ephedrine on cerebral blood flow and cerebral
K. U. Koch, I. Mikkelsen, Joel Aanerud, U. Espelund, A. Tietze, G. Oettingen, N. Juul, L. Nikolajsen, L. Østergaard, M. Rasmussen   +9 more
semanticscholar   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed-Dose Combination Tablets in Healthy Chinese Volunteers. [PDF]

Clin Pharmacol Drug Dev
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Ye M, Zhang R, Wan J, Zhou J, Guo P, Yu D, Li P, Liu Y, Shi S.   +8 more
europepmc   +2 more sources

Effect of intravenous phenylephrine infusion on dose requirement of intrathecal plain levobupivacaine for cesarean section: A placebo-controlled preliminary study

Saudi Journal of Anaesthesia, 2017
Background: Phenylephrine infusion has been shown to decrease rostral spread of plain and hyperbaric local anesthetic (LA) when compared to ephedrine infusion.
Asha Tyagi, Aanchal Kakkar, Namrata Niwal, Medha Mohta, Ashok Kumar Sethi   +4 more
doaj   +1 more source

A randomised controlled trial of phenylephrine and noradrenaline boluses for treatment of postspinal hypotension during elective caesarean section

Anaesthesia, 2019
Phenylephrine is currently the vasopressor of choice during elective caesarean section, but it can cause reflex bradycardia. Noradrenaline, a potent α‐agonist and weak β‐agonist, may be associated with a lower incidence of bradycardia.
M. Mohta, A. Garg, G. Chilkoti, R. Malhotra   +3 more
semanticscholar   +1 more source