Results 51 to 60 of about 66,253 (217)

Comparing Topical Mydriatics Effectiveness in Preserving Pupil Dilation during Small-incision Cataract Surgery

Journal of Pharmaceutical Research
Background: Pupil dilation using topical mydriatics is one of the important pre-requisites prior to performing cataract surgery. There are various mechanisms through which mydriasis can be achieved.
Aastha Shukla, Vikas Kamat, Pramod Wartha, Milind Sonone   +3 more
doaj   +1 more source

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

British Journal of Pharmacology, EarlyView.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu, Yanyan Zhang, Meiling Shan, Jiaqi Cao, Zihan Fan, Zhaoxia Xu, Xiaozhen Ding, Xiaodong Liu, Lijun Shi   +8 more
wiley   +1 more source

Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats

Brazilian Journal of Medical and Biological Research, 2001
Ouabain increases vascular resistance and may induce hypertension by inhibiting the Na+ pump. The effects of 0.18 and 18 µg/kg, and 1.8 mg/kg ouabain pretreatment on the phenylephrine (PHE; 0.1, 0.25 and 0.5 µg, in bolus)-evoked pressor responses were ...
L.V. Rossoni, V.D. Pinto, D.V. Vassallo
doaj   +1 more source

Clinical comparison of prophylactic phenylephrine infusion vs. bolus regimens on maternal hemodynamics and neonatal outcomes during cesarean section

Journal of Obstetric Anaesthesia and Critical Care, 2020
Background and Objective: Phenylephrine bolus or infusion is used to maintain arterial blood pressure during the subarachnoid block (SAB) for cesarean section.
Nitesh Kumar, Mathews Jacob, Priya Taank, Shalendra Singh, Neetika Tripathi   +4 more
doaj   +1 more source

Permanent tracheostomy meets 3D‐printing: Surgical technique and innovation

Equine Veterinary Education, EarlyView.
Summary This clinical commentary serves to accompany the recent case report from Debald et al. (2025) detailing the use of a removable, custom, 3D‐printed implant to manage a dynamically collapsing, permanent tracheal stoma. This creative use of an increasingly common technology provided a cost‐effective manner to successfully manage the complications ...
D. Major
wiley   +1 more source

Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses

Equine Veterinary Education, EarlyView.
Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley   +1 more source

Particle size reduction to the nanometer range: a promising approach to improve buccal absorption of poorly water-soluble drugs

International Journal of Nanomedicine, 2011
Shasha Rao, Yunmei Song, Frank Peddie, Allan M EvansSansom Institute for Health Research, Division of Health Sciences, University of South Australia, Adelaide, South Australia, AustraliaAbstract: Poorly water-soluble drugs, such as phenylephrine, offer ...
Rao S, Song Y, Peddie F, Evans AM
doaj  

Phenylephrine, a common cold remedy active ingredient, suppresses uterine contractions through cAMP signalling

Scientific Reports, 2018
Regulation of uterine contractility is an important aspect of women’s health. Phenylephrine, a selective agonist of the α1-adrenoceptor and a potent smooth muscle constrictor, is widely used in women even during pregnancy to relieve cold-related symptoms,
Xingjuan Chen, Marya Meroueh, Gabriela Mazur, Evan Rouse, K. Hundal, Christopher W. Stamatkin, A. Obukhov   +6 more
semanticscholar   +1 more source

Beyond Tumor Control: A Protocol for Multidimensional Assessment of Long‐Term Effects of Intensity‐Modulated Radiotherapy on Vision, Patient Well‐Being, and Morbidity in Head and Neck Cancer

Med Research, EarlyView.
Benjamin Abaidoo, Hannah Ayettey, Andrew Elikem Akafo, Naa N. Tagoe, Mildred Johnson, Vera Adobea Essuman, Edith Dogbe   +6 more
wiley   +1 more source

Pregabalin contributes to increased recovery time from isoflurane anaesthesia for magnetic resonance imaging in horses

Equine Veterinary Journal, EarlyView.
Abstract Background Pregabalin reduces excitatory neurotransmitter release and is used for anxiolysis in humans, cats, and horses. The effects of pregabalin on equine recovery following isoflurane anaesthesia are unknown. Objectives To determine if pre‐anaesthetic oral pregabalin influences recovery time and/or quality from isoflurane anaesthesia in ...
Abigail Blanton, Kati G. Glass, Jeanette Bayer, Courtney Baetge, Ryota Watanabe, Sarah N. Sampson, Mauricio Lépiz, Kara Moreno, Keila K. Ida   +8 more
wiley   +1 more source