Results 51 to 60 of about 63,750 (296)

The left ventricular contractility of the rat heart is modulated by changes in flow and a1-adrenoceptor stimulation

Brazilian Journal of Medical and Biological Research, 1998
Myocardial contractility depends on several mechanisms such as coronary perfusion pressure (CPP) and flow as well as on a1-adrenoceptor stimulation. Both effects occur during the sympathetic stimulation mediated by norepinephrine.
P.F. Vassallo, I. Stefanon, L.V. Rossoni, P.J.F. Tucci, D.V. Vassallo   +4 more
doaj   +1 more source

The effects on Apgar scores and neonatal outcomes of switching from a combination of phenylephrine and ephedrine to phenylephrine alone as a prophylactic vasopressor during spinal anesthesia for cesarean section [PDF]

Korean Journal of Anesthesiology, 2014
BackgroundEphedrine, unlike phenylephrine, has a dose-related propensity to depress fetal pH during spinal anesthesia during cesarean section. A low arterial umbilical cord pH has a strong association with neonatal mortality and morbidity. The purpose of
Joo Yeon Jeon, In Ho Lee, Young Seok Jee, Pil Moo Lee, Seung In Park, Hea-Jo Yoon   +5 more
doaj   +1 more source

Comparison of phenylephrine and norepinephrine for prevention of hypotension in patients undergoing cesarean section under spinal anesthesia – A randomized prospective study

Journal of Obstetric Anaesthesia and Critical Care, 2022
Background: Hypotension is a common side effect of spinal anesthesia for cesarean section with incidence of upto 71%. Various vasopressors are available for counteracting spinal hypotension each with different pharmacological profile.
Wakhloo Renu, Bhagat Heena, Gandotra Megha, Suri Era   +3 more
doaj   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

British Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan, Katherine Z. Isoardi, Darren M. Roberts, Ong Sook Har   +3 more
wiley   +1 more source

The pressor and mydriatic effects of tropicamide-phenylephrine combination, plain tropicamide, and plain phenylephrine

Philippine Journal of Ophthalmology, 2005
Objective: To evaluate the pressor and mydriatic effects of different concentrations of tropicamide and phenylephrine eye drops: tropicamide 0.5% (Mydriacyl), phenylephrine hydrochloride 2.5% (Mydfrin), tropicamide-phenylephrine combination 0.5%/0.5 ...
Marion Alva Mesina-Bayana, MD, Milagros H. Arroyo, MD   +1 more
doaj  

Comparison of efficacy Ephedrine and phenylephrine in Postoperative Vomiting in Cesarean section [PDF]

, 2013
Introduce: Postoperative nausea and vomiting (PONV) still is the most big problem event encountered in the PACU (Post Anesthesia Care Unit), despite advances in prevention and treatment.
Ahmadi, M., Ameri, M.A., Hassanzad, A., Kashani, E., Mohajer, S.A.M.   +4 more
core  

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Effect of co-administration of different doses of phenylephrine with oxytocin on the prevention of oxytocin-induced hypotension in caesarean section under spinal anaesthesia: A randomised comparative study

Indian Journal of Anaesthesia, 2017
Introduction: Co-administration of phenylephrine prevents oxytocin-induced hypotension during caesarean section under spinal anaesthesia (SA), but higher doses cause reflex bradycardia.
Ranjitha Gangadharaiah, Devika Rani Duggappa, Sudheesh Kannan, S B Lokesh, Karuna Harsoor, K M Sunanda, S S Nethra   +6 more
doaj   +1 more source

SARM1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure by Enhancing NAD⁺ Metabolism. [PDF]

FASEB J
Under pathological conditions, elevated hydrolytic activity of SARM1 significantly depletes NAD+ levels and compromises electron transport chain (ETC) function. This disruption induces mitochondrial dysfunction, elevates ROS production, reduces ATP synthesis, and increases inflammation, which collectively accelerate cardiac hypertrophy (CH) and ...
Shi HT, Zhao GJ, Liu SJ, Du BB, Xiao LL, Huang Z, Zhang DH, Wu LM, Lu YY, Du QG, Wang EK, Zhang YZ.   +11 more
europepmc   +2 more sources

Phenylephrine: in or out?

Southern African Journal of Anaesthesia and Analgesia, 2011
Phenylephrine is a synthetic, non-catecholamine, redominantly α-adrenergic agonist when used at clinically relevant dosages. It does have some β-effects, but only at very high doses.
openaire   +2 more sources