Results 51 to 60 of about 66,103 (276)
Life Sciences, Medicine and Biomedicine, 2018 The general notion of activation of Gq-protein coupled receptors involves the mobilisation of stored and extracellular calcium and leads to smooth muscle tissue contraction.
Kayatri Govindaraju +3 more
doaj +1 more source
Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia [PDF]
, 2015 Deletion of exon 9 from Cullin‐3 (CUL3, residues 403–459: CUL3Δ403–459) causes pseudohypoaldosteronism type IIE (PHA2E), a severe form of familial hyperkalaemia and hypertension (FHHt).
Al Maskari, Raya S. +14 more
core +4 more sources
Novel Simplified Nasal Endoscopy Grading System for Hereditary Hemorrhagic Telangiectasia Patients
The Laryngoscope, EarlyView.We validated a novel, simplified nasal endoscopy grading system for patients with Hereditary Hemorrhagic Telangiectasia (HHT). Our grading (mild, moderate, severe) demonstrated strong correlation with Epistaxis Severity Score (ESS) and Quality of Life (QoL), and showed substantial inter‐rater reliability (ICC = 0.8).
Ethan Soudry +4 more
wiley +1 more source
Philippine Journal of Ophthalmology, 2005 Objective: To evaluate the pressor and mydriatic effects of different concentrations of tropicamide and phenylephrine eye drops: tropicamide 0.5% (Mydriacyl), phenylephrine hydrochloride 2.5% (Mydfrin), tropicamide-phenylephrine combination 0.5%/0.5 ...
Marion Alva Mesina-Bayana, MD +1 more
doaj
Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]
, 2016 Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed +5 more
core +2 more sources
Clinical approach to the selection of topical decongestants in paediatric otolaryngology practice
Медицинский совет, 2019 This article describes the mechanism of action of topical decongestants from the perspective of their efficient and safe use in paediatric otorhinolaryngology.
S. A. Karpishchenko +2 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Purpose: Studies involving mouse models and human uterine smooth muscle cells have shown that phenylephrine inhibits uterine contractions in non-pregnant mice and human in vitro cell via cyclic adenosine monophosphate (cAMP) signaling. However, there has
Yao-Hua Shen +7 more
doaj +1 more source
Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years. [PDF]
, 2008 This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal ...
Chelvanayagam, Sonya +2 more
core +1 more source
VIEW, EarlyView.Inhibiting the SUMOylation modification of TRPM4 can prevent the vascular endothelial damage caused by ATO. Inhibition of TRPM4 SUMOylation, either pharmacologically by GA or genetically by the K618R mutation, protects against ATO‐induced vascular endothelial damage.
Ting‐Ting Tong +18 more
wiley +1 more source
The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [PDF]
, 2008 The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endothelium in response to acetylcholine (ACh) passively ...
Frantisek Kristek +5 more
core +1 more source