Results 31 to 40 of about 7,613 (182)

Achados audiológicos em crianças com fenilcetonúria Audiologic findings in children with phenylketonuria

open access: yesRevista da Sociedade Brasileira de Fonoaudiologia, 2010
OBJETIVO: Investigar a existência de alterações na audição de crianças com fenilcetonúria diagnosticadas e tratadas precocemente e comparar os resultados com os encontrados nas avaliações auditivas de crianças normais de mesma idade.
Patrícia Cotta Mancini   +5 more
doaj   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

PKU: attention and executive profile in early detected and adequately treated patients [PDF]

open access: yes, 2021
Antecedentes: Los pacientes fenilcetonúricos, incluso adecuadamente diagnosticados y tratados, pueden resultar con disfunción neurocognitiva. Objetivo: Evaluar la neurocognición de niños fenilcetonúricos y su relación con variables de la enfermedad y su ...
Chiesa, Ana Elena   +3 more
core  

Gradient Ion Beams Regulate Surface Group Modification to Enhance Interfacial Charge Transport in Triboelectric Polymers

open access: yesAdvanced Science, EarlyView.
This study addresses the core scientific question of atomic‐scale structural units and their assembly mechanisms by integrating ion implantation technology— originally developed in nuclear physics research—with flexible intelligent polymers. Through this interdisciplinary approach, we have enabled on‐demand customization of surface functionalities and ...
Yi Chen   +11 more
wiley   +1 more source

Achieving Chemical Accuracy in Cyclodextrin Host–Guest Binding via Integrative Atomistic Modelling

open access: yesAdvanced Science, EarlyView.
A generalizable computational framework is presented that overcomes long‐standing challenges in modelling cyclodextrin host‐guest binding by integrating host‐specific force‐field refinement, equilibrium enhanced sampling, nonequilibrium alchemical switching, convolution sampling of independent works, rigorous finite‐size corrections, and QM‐based ...
Xiaohui Wang   +7 more
wiley   +1 more source

Reconfigurable Acoustofluidic Microvortices for Selective Microcargo Delivery

open access: yesAdvanced Science, EarlyView.
This work introduces a frequency‐encoded, reconfigurable acoustofluidic system that overcomes the low throughput and poor selectivity of conventional micro‐delivery methods. By exploiting discrete microbubble resonances to program adaptive microvortex modes, the platform enables real‐time switching and selective guidance of microscale payloads through ...
Lei Wang   +6 more
wiley   +1 more source

Efficient and Robust Heterostructure CeZrOx/NiO‐Ni Inverse Catalyst for Sustainable Photothermal CO2 Methanation

open access: yesAdvanced Science, EarlyView.
A heterostructured CeZrOx/NiO‐Ni inverse catalyst is designed for highly efficient photothermal CO2 methanation under low‐intensity light without auxiliary heating. It achieves 464 mmol·gcat−1·h−1 methane space‐time yield under natural concentrated sunlight, maintains stability over light‐dark cycles and extended air storage, and is scalable to 100 g ...
Chuqiao Song   +16 more
wiley   +1 more source

The European challenges of funding orphan medicinal products [PDF]

open access: yes, 2018
Funding of orphan medicinal products (OMPs) is an increasing challenge in the European Union (EU).To identify the different methods for public funding of OMPs in order to map the availability for rare disease patients, as well as to compare the public ...
Arickx, Francis   +14 more
core   +4 more sources

Study of Resistive Switching Dynamics and Memory States Equilibria in Analog Filamentary Conductive‐Metal‐Oxide/HfOx ReRAM via Compact Modeling

open access: yesAdvanced Electronic Materials, EarlyView.
A physics‐based compact model for Conductive‐Metal‐Oxide/HfOx ReRAM, accounting for ion dynamics, electronic conduction, and thermal effects, is presented. Accurate and versatile simulations of analog non‐volatile conductance modulation and memory state stabilization enable reliable circuit‐level studies, advancing the optimization of neuromorphic and ...
Matteo Galetta   +9 more
wiley   +1 more source

Insights from meta‐analysis for efficient docosahexaenoic acid production in thraustochytrids through advanced cultivation and fermentation strategies

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract This systematic review examines strategies for docosahexaenoic acid (DHA) production by thraustochytrids, focusing on cultivation techniques, fermentation technologies, and carbon/nitrogen optimization to increase productivity. Among 169 eligible articles, the 100 most productive studies (0.7–10.3 g DHA L−1 per day) were analyzed. Quantitative
Jhiovana Cristielly Carrera Silva da Costa   +6 more
wiley   +1 more source

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